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成分词典

成分词典

RESORCINOL

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3.

分子结构

产品中实际含有多少

暂无产品标示该成分含量。

含该成分的产品中,7 款将其列在 1% 线之前,5 款列在之后(通常不超过 1%)。

含有此成分的产品

已确认 10 款中的 10 款 · 按含量充足程度排序

定义

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3. It has a role as a sensitiser and an erythropoietin inhibitor. It is a phenolic donor, a benzenediol and a member of resorcinols.

来源: PubChem

美国FDA 物质登记 · UNII YUL4LO94HK · 登记名称 Resorcinol · 单一化学物质

来源: 美国FDA 物质识别码(UNII)

Resorcinol is the phenol that conforms to the formula

化妆品中的作用

染发HAIR DYEING延缓产品因氧化变质ANTIOXIDANT为产品增添香味PERFUMING使酒精不可饮用DENATURANT

安全与法规参考

限用
韩国 · 英国

来源: 东盟化妆品指令 · 欧盟化妆品法规 · 加拿大禁用·限用成分清单 · 韩国食药处 化妆品法规信息 · 台湾FDA 化妆品成分 · 台湾FDA 化妆品法规 · 英国化妆品法规

阿根廷 · 巴西

  • Field of application and/or use : (a) oxidation dye for coloring hair: 1. General use 2. Professional use b) Shampoos and hair lotions
  • Maximum concentration permitted at final product : a) to 5% b) 0.5%
  • Use conditions and warnings that must appear on the label : a - 1. - Contains resorcinol - Rinse hair well after application - Do not use on eyelashes or eyebrows - Rinse eyes immediately if the product comes in contact with them a - 2. - For professional use only - Contains resorcinol - Rinse eyes immediately if the product comes in contact with them b. - Contains resorcinol

东盟

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. (b) Hair lotions and shampoos
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.5%
  • Other limitations and requirements : For (a): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.25 % The direction for use “wear suitable gloves” must be included in label or leaflet text
  • Conditions of use and warning which must be printed on the labels : (a) To be printed on the label: The mixing ratio. “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows.” (b) Contains resorcinol

加拿大

  • Conditions of Use by product type : Not permitted in cosmetics intended for use on the skin. Additionally see "Coal tar dye."

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : (a)氧化性染髮產品 : 1.25%
  • (b)髮用乳(液)及洗髮產品 : 0.5%

日本

  • 每100g最大配合量(Maximum amount of ingredient per 100 g) : 0.10 g(0.10 g)

中国

  • 最大配合量 : 0.5%
  • 最大配合量 : 1.25%

欧盟

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos
  • Maximum concentration in ready for use preparation : (c) 0.5%
  • Other : (For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyeslashes must not exceed 1,25 % (b) Professional use only
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows” (b) To be printed on the label: The mixing ratio. “For professional use only Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Wear suitable gloves”

来源: 韩国食药处 化妆品法规信息

韩国有毒物质 GHS 分类: 警告 · H302 (第4类) · H412 (第3类) · H400 (第1类) · 另有 3 项

来源: 韩国有毒物质 GHS 信息(环境公团)

欧盟化妆品法规 附录III(限用物质) 第22项 · 最高浓度 (c) 0,5% · 适用 (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos

来源: 欧盟限用成分(附录III)

Restriction III/22 · SCCS opinion: Opinion on Resorcinol; OPINION on Resorcinol

来源: 欧盟 CosIng 成分清单

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2005/2006

来源: 美国CIR 安全性评估

Reviewed by CIR: Final Report on the Safety Assessment of 2-Methylresorcinol and Resorcinol

来源: 美国CIR 安全性评估

详细资料——标示名称、识别编号、物性、试验记录、文献

官方标示名称和定义

日本化妆品工业联合会标示名称 レゾルシン: 本品は、次の化学式で表される芳香族化合物である。

来源: 日本化妆品工业联合会标示名称

别名和识别信息

RESORCINOLINCI레조시놀韩国标示名称(食药处标准名)1,3-Benzenediol同义名レゾルシン日本标示名称
CAS No.化学物质登记号
108-46-3
EC No.欧盟化学品目录编号
203-585-2
DTXSID美国EPA化学品编号
DTXSID2021238
DTXCID美国EPA化合物编号
DTXCID601238
IUPAC
Benzene-1,3-diol
分子式
C6H6O2
分子量
110.112 g/mol

实测物性

性状
Resorcinol is a very white crystalline solid that becomes pink on exposure to light if not completely pure. Burns although ignition is difficult. Density approximately 1.28 g / cm3. Irritating to skin and eyes. Toxic by skin absorption. Used to make plastics and pharmaceuticals. · Other Solid, Dry Powder, CBI, Large Crystals
气味
Faint, characteristic odor
沸点
531 to 536 °F at 760 mmHg (NTP, 1992) · 280 °C, but volatilizes at lower temperature and is slightly volatile with steam
熔点
228 to 232 °F (NTP, 1992) · 109.8 °C
溶解性
greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992) · In water, 7.17X10+5 mg/L at 25 °C
嗅觉阈值
6 (mg/L)
pH
5.2
熔点/凝固点
110 ℃
初沸点和沸程
280 ℃
闪点
127 ℃(c.c.)
燃烧或爆炸范围上限/下限
%
蒸气压
0.065 ㎩ (20℃)
溶解度
71.7 g/100㎖ (25℃)
蒸气密度
3.79
比重
1.2717
正辛醇/水分配系数(Kow)
0.80
自燃温度
607 ℃
黏度
3.76 (141 C)
分子量
110.11

这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。

来源: PubChem · 韩国安全保健公团 安全数据表

产品实际使用的用途

这是向美国 EPA 申报含该成分的 39 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。

  • Dye5
  • Biocide5
  • Flavouring and nutrient3
  • Fragrance3
  • Adhesion/cohesion promoter3
  • Binder3
  • Pharmaceutical (EPA)2
  • Intermediate2
其余用途 11 项
  • Solvent2
  • Monomers2
  • Conductive agent1
  • Stabilizing agent1
  • Deodorizer1
  • UV stabilizer1
  • Elasticizer1
  • Chemical reaction regulator1
  • Polymerization promoter1
  • Flame retardant1
  • Antioxidant1

来源: 美国EPA CompTox

刺激与致敏试验记录

记录有皮肤试验 8 项、眼部试验 6 项。

归类为中等1 项

试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。

查看全部 14 项试验
  • Category 1
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Category 2
    Skin Irritation · Screening
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 0 (A00), 1, 5, 10, 25 and 50% w/v resorcinol
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) Concentration: 2.5 % according to
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · other guideline: according to
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · other guideline: FHSLA according to
  • Category 1
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative

来源: 美国EPA CompTox

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