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Ingredients

Ingredient Dictionary

RESORCINOL

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 7 list it before the 1% line and 5 after it (usually 1% or less).

Products using this ingredient

10 of 10 confirmed · likeliest to carry enough first

Definition

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3. It has a role as a sensitiser and an erythropoietin inhibitor. It is a phenolic donor, a benzenediol and a member of resorcinols.

Source: PubChem

US FDA substance register · UNII YUL4LO94HK · registered name Resorcinol · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Resorcinol is the phenol that conforms to the formula

Cosmetic roles

Dyes hairHAIR DYEINGSlows spoilage by oxygenANTIOXIDANTGives the product a scentPERFUMINGMakes alcohol undrinkableDENATURANT

Safety & regulatory references

Restricted
South Korea · Taiwan · United Kingdom

Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information · Taiwan FDA cosmetic ingredients · Taiwan FDA cosmetic regulations · UK cosmetics regulations (OPSS)

Argentina · Brazil

  • Field of application and/or use : (a) oxidation dye for coloring hair: 1. General use 2. Professional use b) Shampoos and hair lotions
  • Maximum concentration permitted at final product : a) to 5% b) 0.5%
  • Use conditions and warnings that must appear on the label : a - 1. - Contains resorcinol - Rinse hair well after application - Do not use on eyelashes or eyebrows - Rinse eyes immediately if the product comes in contact with them a - 2. - For professional use only - Contains resorcinol - Rinse eyes immediately if the product comes in contact with them b. - Contains resorcinol

ASEAN

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. (b) Hair lotions and shampoos
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.5%
  • Other limitations and requirements : For (a): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.25 % The direction for use “wear suitable gloves” must be included in label or leaflet text
  • Conditions of use and warning which must be printed on the labels : (a) To be printed on the label: The mixing ratio. “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows.” (b) Contains resorcinol

Canada

  • Conditions of Use by product type : Not permitted in cosmetics intended for use on the skin. Additionally see "Coal tar dye."

Japan

  • Maximum amount per 100 g(Maximum amount of ingredient per 100 g) : 0.10 g(0.10 g)

China

  • Maximum concentration : 0.5%
  • Maximum concentration : 1.25%

European Union

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos
  • Maximum concentration in ready for use preparation : (c) 0.5%
  • Other : (For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyeslashes must not exceed 1,25 % (b) Professional use only
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows” (b) To be printed on the label: The mixing ratio. “For professional use only Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Wear suitable gloves”

Source: MFDS (Korea) cosmetic regulatory information

Korea’s toxic-substance GHS classification: Warning · H302 (category 4) · H412 (category 3) · H400 (category 1) · +3 more

Source: Korea toxic substances GHS register (NIER)

EU Cosmetics Regulation, Annex III (restricted substances), entry 22 · maximum concentration (c) 0,5% · applies to (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos

Source: EU restricted substances (Annex III)

Restriction III/22 · SCCS opinion: Opinion on Resorcinol; OPINION on Resorcinol

Source: EU CosIng ingredient list

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2005/2006

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of 2-Methylresorcinol and Resorcinol

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name レゾルシン: 本品は、次の化学式で表される芳香族化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

RESORCINOLINCI레조시놀Korean label name (MFDS standard)1,3-BenzenediolSynonymレゾルシンJapanese labelling name
CAS No.chemical registry number
108-46-3
EC No.EU chemical inventory number
203-585-2
DTXSIDUS EPA chemical ID
DTXSID2021238
DTXCIDUS EPA compound ID
DTXCID601238
IUPAC
Benzene-1,3-diol
Molecular formula
C6H6O2
Molecular weight
110.112 g/mol

Measured properties

Appearance
Resorcinol is a very white crystalline solid that becomes pink on exposure to light if not completely pure. Burns although ignition is difficult. Density approximately 1.28 g / cm3. Irritating to skin and eyes. Toxic by skin absorption. Used to make plastics and pharmaceuticals. · Other Solid, Dry Powder, CBI, Large Crystals
Odour
Faint, characteristic odor
Boiling point
531 to 536 °F at 760 mmHg (NTP, 1992) · 280 °C, but volatilizes at lower temperature and is slightly volatile with steam
Melting point
228 to 232 °F (NTP, 1992) · 109.8 °C
Solubility
greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992) · In water, 7.17X10+5 mg/L at 25 °C
Odour threshold
6 (mg/L)
pH
5.2
Melting/freezing point
110 ℃
Initial boiling point and range
280 ℃
Flash point
127 ℃(c.c.)
Upper/lower flammability or explosive limits
%
Vapour pressure
0.065 ㎩ (20℃)
Water solubility
71.7 g/100㎖ (25℃)
Vapour density
3.79
Relative density
1.2717
n-Octanol/water partition coefficient (Kow)
0.80
Auto-ignition temperature
607 ℃
Viscosity
3.76 (141 C)
Molecular weight
110.11

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 39 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Dye5
  • Biocide5
  • Flavouring and nutrient3
  • Fragrance3
  • Adhesion/cohesion promoter3
  • Binder3
  • Pharmaceutical (EPA)2
  • Intermediate2
11 other uses
  • Solvent2
  • Monomers2
  • Conductive agent1
  • Stabilizing agent1
  • Deodorizer1
  • UV stabilizer1
  • Elasticizer1
  • Chemical reaction regulator1
  • Polymerization promoter1
  • Flame retardant1
  • Antioxidant1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

8 skin studies and 6 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 14 studies
  • Category 1
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Category 2
    Skin Irritation · Screening
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 0 (A00), 1, 5, 10, 25 and 50% w/v resorcinol
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) Concentration: 2.5 % according to
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · other guideline: according to
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · other guideline: FHSLA according to
  • Category 1
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative

Source: US EPA CompTox dashboard

Related literature

Linked databases 33