Gloshell
成分辞典

成分辞典

レゾルシン

RESORCINOL

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3.

分子構造

製品には実際どれくらい入っているか

この成分の含有量を表示した製品はまだありません。

この成分を含む製品のうち7件は全成分の前の方(1%ラインより前)、5件は後ろ(ふつう1%以下)に書いています。

この成分を含む製品

確認済み 10件中 10件 · 十分に入っている製品から

定義

Resorcinol is a benzenediol that is benzene dihydroxylated at positions 1 and 3. It has a role as a sensitiser and an erythropoietin inhibitor. It is a phenolic donor, a benzenediol and a member of resorcinols.

出典: PubChem

米国FDA 物質登録 · UNII YUL4LO94HK · 登録名 Resorcinol · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

Resorcinol is the phenol that conforms to the formula

化粧品での役割

髪を染めるHAIR DYEING酸素による劣化を遅らせるANTIOXIDANT製品に香りをつけるPERFUMINGアルコールを飲用不可にするDENATURANT

安全性・規制情報

制限
イギリス · 韓国

出典: ASEAN 化粧品指令 · EU 化粧品規則 · カナダ 禁止・制限成分リスト · 韓国食薬処 化粧品規制情報 · 台湾FDA 化粧品成分 · 台湾FDA 化粧品規制 · 英国 化粧品規則

アルゼンチン · ブラジル

  • Field of application and/or use : (a) oxidation dye for coloring hair: 1. General use 2. Professional use b) Shampoos and hair lotions
  • Maximum concentration permitted at final product : a) to 5% b) 0.5%
  • Use conditions and warnings that must appear on the label : a - 1. - Contains resorcinol - Rinse hair well after application - Do not use on eyelashes or eyebrows - Rinse eyes immediately if the product comes in contact with them a - 2. - For professional use only - Contains resorcinol - Rinse eyes immediately if the product comes in contact with them b. - Contains resorcinol

ASEAN

  • Field of application and/or use : (a) Hair dye substance in oxidative hair dye products Use for dyeing eyelashes and eyebrows is not permitted. (b) Hair lotions and shampoos
  • Maximum authorised concentration in the finished cosmetic product : (b) 0.5%
  • Other limitations and requirements : For (a): After mixing under oxidative conditions the maximum concentration applied to hair must not exceed 1.25 % The direction for use “wear suitable gloves” must be included in label or leaflet text
  • Conditions of use and warning which must be printed on the labels : (a) To be printed on the label: The mixing ratio. “Hair colorants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: - you have a rash on your face or sensitive, irritated and damaged scalp, - you have ever experienced any reaction after colouring your hair, - you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains resorcinol. Rinse hair well after application. Rinse eyes immediately if product comes into contact with them. Do not use to dye eyelashes or eyebrows.” (b) Contains resorcinol

カナダ

  • Conditions of Use by product type : Not permitted in cosmetics intended for use on the skin. Additionally see "Coal tar dye."

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : (a)氧化性染髮產品 : 1.25%
  • (b)髮用乳(液)及洗髮產品 : 0.5%

日本

  • 100gあたりの最大配合量(Maximum amount of ingredient per 100 g) : 0.10 g(0.10 g)

中国

  • 最大配合量 : 0.5%
  • 最大配合量 : 1.25%

欧州連合

  • Product Type, body parts : (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos
  • Maximum concentration in ready for use preparation : (c) 0.5%
  • Other : (For (a) and (b): After mixing under oxidative conditions the maximum concentration applied to hair or eyeslashes must not exceed 1,25 % (b) Professional use only
  • Wording of conditions of use and warnings : (a) To be printed on the label: The mixing ratio. “ Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Do not use to dye eyelashes or eyebrows” (b) To be printed on the label: The mixing ratio. “For professional use only Hair colourants can cause severe allergic reactions. Read and follow instructions. This product is not intended for use on persons under the age of 16. Temporary ‘black henna’ tattoos may increase your risk of allergy. Do not colour your hair if: — you have a rash on your face or sensitive, irritated and damaged scalp, — you have ever experienced any reaction after colouring your hair, — you have experienced a reaction to a temporary ‘black henna’ tattoo in the past. Contains phenylenediamines. Wear suitable gloves”

出典: 韓国食薬処 化粧品規制情報

韓国の有害物質GHS分類: 警告 · H302 (区分4) · H412 (区分3) · H400 (区分1) · ほか3件

出典: 韓国 有害物質GHS情報(環境公団)

EU化粧品規則 附属書III(制限物質) 第22項 · 最大濃度 (c) 0,5% · 適用 (a) Hair dye substance in oxidative hair dye products (b) Products intended for colouring eyelashes (c) Hair lotions and shampoos

出典: EU 制限成分(附属書III)

Restriction III/22 · SCCS opinion: Opinion on Resorcinol; OPINION on Resorcinol

出典: EU CosIng 成分リスト

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments: 2005/2006

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of 2-Methylresorcinol and Resorcinol

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

公式表示名・定義

日本化粧品工業会の表示名称 レゾルシン: 本品は、次の化学式で表される芳香族化合物である。

出典: 日本化粧品工業会 表示名称

別名・識別情報

RESORCINOLINCI레조시놀韓国の表示名(食薬処標準名)1,3-Benzenediol別名レゾルシン日本の表示名称
CAS No.化学物質登録番号
108-46-3
EC No.EU化学物質目録番号
203-585-2
DTXSID米国EPA化学物質番号
DTXSID2021238
DTXCID米国EPA化合物番号
DTXCID601238
IUPAC
Benzene-1,3-diol
分子式
C6H6O2
分子量
110.112 g/mol

測定された物性

性状
Resorcinol is a very white crystalline solid that becomes pink on exposure to light if not completely pure. Burns although ignition is difficult. Density approximately 1.28 g / cm3. Irritating to skin and eyes. Toxic by skin absorption. Used to make plastics and pharmaceuticals. · Other Solid, Dry Powder, CBI, Large Crystals
臭い
Faint, characteristic odor
沸点
531 to 536 °F at 760 mmHg (NTP, 1992) · 280 °C, but volatilizes at lower temperature and is slightly volatile with steam
融点
228 to 232 °F (NTP, 1992) · 109.8 °C
溶解性
greater than or equal to 100 mg/mL at 65.3 °F (NTP, 1992) · In water, 7.17X10+5 mg/L at 25 °C
臭いの閾値
6 (mg/L)
pH
5.2
融点・凝固点
110 ℃
初留点および沸点範囲
280 ℃
引火点
127 ℃(c.c.)
燃焼・爆発範囲の上限/下限
%
蒸気圧
0.065 ㎩ (20℃)
溶解度
71.7 g/100㎖ (25℃)
蒸気密度
3.79
比重
1.2717
n-オクタノール/水分配係数(Kow)
0.80
自然発火温度
607 ℃
粘度
3.76 (141 C)
分子量
110.11

物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品39件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Dye5
  • Biocide5
  • Flavouring and nutrient3
  • Fragrance3
  • Adhesion/cohesion promoter3
  • Binder3
  • Pharmaceutical (EPA)2
  • Intermediate2
その他の用途 11件
  • Solvent2
  • Monomers2
  • Conductive agent1
  • Stabilizing agent1
  • Deodorizer1
  • UV stabilizer1
  • Elasticizer1
  • Chemical reaction regulator1
  • Polymerization promoter1
  • Flame retardant1
  • Antioxidant1

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験8件・眼試験6件の記録があります。

中程度と分類1件

試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験14件をすべて見る
  • Category 1
    Skin Sensitization · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Category 2
    Skin Irritation · Screening
  • Category 6.3A (Category 2)
    Skin Irritation · Read Across
  • Skin Irrit. 2
    Skin Irritation · Authoritative
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 0 (A00), 1, 5, 10, 25 and 50% w/v resorcinol
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) Concentration: 2.5 % according to
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · other guideline: according to
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · other guideline: FHSLA according to
  • Category 1
    Eye Irritation · Screening
  • Eye Irrit. 2
    Eye Irritation · Authoritative

出典: 米国EPA CompTox

関連文献

連携データベース 33