Retinyl acetate is an acetate ester.
How much products actually contain
2 products state the amountmedian 0.00005%
- under 0.01% 2
- 0.01–0.1% 0
- 0.1–1% 0
- 1% or more 0
Amounts are mostly stated by products named after the ingredient, so they may lean towards token amounts.
Of the products containing it, 3 list it before the 1% line and 5 after it (usually 1% or less).
Products using this ingredient
8 of 8 confirmed · likeliest to carry enough first
Peace Out SkincarePeace Out Skincare Pore Minimizing Strips
Peace Out SkincarePeace Out Skincare Acne Day Dots
Peace Out SkincarePeace Out Skincare Acne Treatment Dots
TOSOWOONGReal Bakuchiol Retinol Fit0.00005% stated
MEDIPEELMEDIPEEL Retinal Collagen Lifting Cream 50ml0.000007% stated
MEDIPEELRetinal NMN Bounce Shot Eye Cream
MEDIPEELMEDIPEEL Retinal NMN Bounce Shot Eye Cream 15ml
MEDIPEELMEDIPEEL Retinal NMN Bounce Shot Booster 30ml
Definition
Retinyl acetate is an acetate ester. It is functionally related to an all-trans-retinol.
Source: PubChem
US FDA substance register · UNII 3LE3D9D6OY · registered name VITAMIN A ACETATE · single chemical substance
Retinyl Acetate is the ester of Retinol and acetic acid.
Cosmetic roles
Safety & regulatory references
Canada
- Maximum Concentration Permitted : 1.0% retinol equivalents; 1.15% w/w retinyl acetate; 1.83% w/w retinyl palmitate.
European Union
- Product Type, body parts : (a) Body lotion (b) other leave-on and rinse-off products
- Maximum concentration in ready for use preparation : (a) 0,05 % Retinol Equivalent (RE) (b) 0,3 % RE
- Wording of conditions of use and warnings : For any cosmetic product containing Retinol, Retinyl Acetate or Retinyl Palmitate the following, labelling is obligatory: ‘Contains Vitamin A. Consider your daily intake before use’.
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/376 · SCCS opinion: OPINION ON Vitamin A (Retinol, Retinyl Acetate, Retinyl Palmitate)
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 酢酸レチノール: 本品は、酢酸(*)とレチノール(*)のエステルである。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 127-47-9
- EC No.EU chemical inventory number
- 204-844-2
- DTXSIDUS EPA chemical ID
- DTXSID6021240
- DTXCIDUS EPA compound ID
- DTXCID701240
- IUPAC
- O~15~-Acetylretinol
- Molecular formula
- C22H32O2
- Molecular weight
- 328.496 g/mol
Measured properties
- Appearance
- solid
- Vapour pressure
- 0 ㎩ (@ 20 ℃)
- Water solubility
- (&, lt, 10 μg/L @ 20 ℃)
- Vapour density
- 11.34
- Relative density
- 0.9817 (@ 25 ℃)
- n-Octanol/water partition coefficient (Kow)
- 9.4 (@ 25 ℃)
- Auto-ignition temperature
- 395 ℃
- Decomposition temperature
- 120 ℃
- Molecular weight
- 328.48
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pharmaceutical (EPA)4
- Flavouring and nutrient1
- Softener and conditioner1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Source: US EPA CompTox dashboard
Related literature
- Plasma retinol levels and side effects following high-dose retinyl acetate in breast cancer patients. · 1988
- Enhancing transdermal delivery of retinyl acetate via transethosomes with emphasis on the impact of edge activators on penetration, safety, and efficacy · 2025
- Simultaneous determination of benzophenone-3, retinol and retinyl acetate in pig ear skin layers by high-performance liquid chromatography. · 2008
- Growth, morphology, function, and morphogenetic properties of rat renal glomerular epithelial cells in vitro: effects of retinyl acetate. · 1989
- Modulation of involucrin and envelope competence in human keratinocytes by hydrocortisone, retinyl acetate, and growth arrest. · 1983
Linked databases 22
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese