Rhein is a dihydroxyanthraquinone.
Definition
Rhein is a dihydroxyanthraquinone.
Source: PubChem
US FDA substance register · UNII YM64C2P6UX · registered name RHEIN · single chemical substance
Cosmetic roles
Inhibits microbial growthANTIMICROBIAL
More data — names, identifiers, properties, test records, literature
Names & identifiers
RHEININCI
- CAS No.chemical registry number
- 478-43-3
- DTXSIDUS EPA chemical ID
- DTXSID4026000
- DTXCIDUS EPA compound ID
- DTXCID606000
- IUPAC
- 4,5-Dihydroxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid
- Molecular formula
- C15H8O6
- Molecular weight
- 284.223 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Biocide1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 0 eye studies are on record.
Classed as moderate1
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 1 studies
- SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Rhein promotes skin wound healing by activating the PI3K/AKT signaling pathway · 2024
- Rhein promotes the proliferation of keratinocytes by targeting oestrogen receptors for skin ulcer treatment · 2022
- Anti-inflammatory mechanism of rhein in treating asthma based on network pharmacology. · 2020
- Rhein sensitizes human pancreatic cancer cells to EGFR inhibitors by inhibiting STAT3 pathway · 2019
- Rhein sensitizes human colorectal cancer cells to EGFR inhibitors by inhibiting STAT3 pathway · 2019