Ingredient Dictionary

SACCHARIN

Saccharin is a 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position.

How much products actually contain

No product states its amount yet.

Of the products containing it, 66 list it before the 1% line and 28 after it (usually 1% or less).

Products using this ingredient

12 of 93 confirmed · likeliest to carry enough first · See all 93

Definition

Saccharin is a 1,2-benzisothiazole having a keto-group at the 3-position and two oxo substituents at the 1-position. It is used as an artificial sweetening agent. It has a role as a xenobiotic, a sweetening agent and an environmental contaminant. It is a 1,2-benzisothiazole and a N-sulfonylcarboxamide.

Source: PubChem

US FDA substance register · UNII FST467XS7D · registered name Saccharin · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Cares for the mouthORAL CAREListed as a fragrance-composition material (not a claim that it adds scent)FRAGRANCE

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name サッカリン: 本品は、トルエンスルホンアミドの無水物であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

SACCHARININCI사카린Korean label name (MFDS standard)1,2-Benzisothiazol-3(2H)-one, 1,1-dioxideSynonymサッカリンJapanese labelling name

CAS No.chemical registry number: 81-07-2
EC No.EU chemical inventory number: 201-321-0
DTXSIDUS EPA chemical ID: DTXSID5021251
DTXCIDUS EPA compound ID: DTXCID401251

IUPAC: 1H-1lambda~6~,2-Benzothiazole-1,1,3(2H)-trione
Molecular formula: C7H5NO3S
Molecular weight: 183.18 g/mol

Measured properties

Appearance: Saccharin (manufacturing) appears as white crystals. Odorless or faintly aromatic odor. Sweet taste. (NTP, 1992) · Wet Solid
Odour: ODORLESS OR HAS FAINT AROMATIC ODOR.
Boiling point: Sublimes (NTP, 1992) · Sublimes
Melting point: 444 °F (decomposes) (NTP, 1992) · 228 °C decomposes
Solubility: greater than or equal to 100 mg/mL at 75 °F (NTP, 1992) · 1 G SOL IN 2.6 ML WATER, 4.7 ML ALC /CALCIUM SALT/.
Density: 0.828 (NTP, 1992) - Less dense than water, will float · 0.828 g/cu cm at 25 °C
pH: pH of 0.35% aqueous solution: 2.0 · 1.84
Dissociation constant: pKa = 1.31 at 25 °C for the conjugate acid
Colour: white
Melting/freezing point: 224.1~226.6 ℃
Initial boiling point and range: &amp, gt, 250 ℃
Flash point: 161.3 ℃
Flammability (solid, gas): not flammable
Vapour pressure: 0 ㎩ (25℃)
Water solubility: 2.9 g/ℓ (24℃, pH: 1.84)
Vapour density: 0.793 g/㎤
Relative density: 0.828 (25℃)
n-Octanol/water partition coefficient (Kow): -0.024 (log Pow, 25℃)
Decomposition temperature: 228 ℃
Molecular weight: 183.185

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Flavouring and nutrient5
Deodorizer2
Fragrance2
Plating agent1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

3 skin studies and 1 eye studies are on record.

Classed as low4

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 4 studies

Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline:
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to other guideline:
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to