Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine.
How much products actually contain
No product states its amount yet.
Of the products containing it, 22 list it before the 1% line and 37 after it (usually 1% or less).
Products using this ingredient
12 of 59 confirmed · likeliest to carry enough first · See all 59
IGK HairIGK Hair Extra Love Shampoo
IGK HairIGK Hair Extra Love Shampoo Liter
AlodiaAlodia Nutrient Infused Organic Black Soap Wash
PHYSIOGELPhysiogel Red Soothing AI Repair Cream 100ml
IGK HairIGK Hair Extra Love Conditioner
IGK HairIGK Hair Extra Love Conditioner Liter
CNP LaboratoryPropolis Rescue Ampule
The Face ShopUltimate Niacinamide 10% Serum 50ml
OLAPLEXOLAPLEX No.4FINE Bond Maintenance™ Volumizing Shampoo Jumbo
OLAPLEXOLAPLEX No.4FINE Bond Maintenance™ Volumizing Shampoo Travel Size
OLAPLEXOLAPLEX No.5FINE Bond Maintenance™ Volumizing Conditioner Jumbo
OLAPLEXOLAPLEX No.5FINE Bond Maintenance™ Volumizing Conditioner Travel Size
Definition
Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a mouse metabolite, an Escherichia coli metabolite and a human metabolite. It is a N-methyl-amino acid, a member of N-methylglycines and a N-alkylglycine. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion.
Source: PubChem
US FDA substance register · UNII Z711V88R5F · registered name Sarcosine · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name サルコシン: 本品は、次の化学式で表されるアミノ酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 107-97-1
- EC No.EU chemical inventory number
- 203-538-6
- DTXSIDUS EPA chemical ID
- DTXSID1047025
- DTXCIDUS EPA compound ID
- DTXCID9027025
- IUPAC
- N-Methylglycine
- Molecular formula
- C3H7NO2
- Molecular weight
- 89.094 g/mol
Measured properties
- Appearance
- Deliquescent crystals or powder. Has a sweetish taste. (NTP, 1992) · Deliquescent solid, [Merck Index] Cream-colored hygroscopic solid, [NTP] White odorless crystalline powder, Hygroscopic, [Alfa Aesar MSDS]
- Melting point
- 406 °F (Decomposes) (NTP, 1992) · 208 °C
- Solubility
- greater than or equal to 100 mg/mL at 61 °F (NTP, 1992) · 300.0 mg/mL
- Colour
- white
- Melting/freezing point
- 63 ℃
- Initial boiling point and range
- 185 ℃
- Flash point
- &, gt, 100 ℃
- n-Octanol/water partition coefficient (Kow)
- -2.80
- Decomposition temperature
- 208-215 ℃
- Molecular weight
- 89.09
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner3
Source: US EPA CompTox dashboard
Related literature
- Engineered Antifouling Peptides with Sarcosine Branches for Robust Electrochemical Detection of the HER2 Biomarker in Real Biological Samples. · 2025
- Sarcosine May Induce EGF Production or Inhibit the Decline in EGF Concentrations in Patients with Chronic Schizophrenia (Results of the PULSAR Study) · 2023
- TMEFF2 AND SARDH COOPERATE TO MODULATE ONE CARBON METABOLISM AND INVASION OF PROSTATE CANCER CELLS · 2013
- Sarcosine induces increase in HER2/neu expression in androgen-dependent prostate cancer cells · 2011
- The Tumor Suppressor Activity of the Transmembrane Protein with Epidermal Growth Factor and Two Follistatin Motifs 2 (TMEFF2) Correlates with Its Ability to Modulate Sarcosine Levels* · 2011
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata 2