SH-OLIGOPEPTIDE-1
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E.
- 韓国の配合上限
- 0.001%
製品には実際どれくらい入っているか
含有量を表示した製品 46件中央値 0.000005%
- 0.01%未満 46
- 0.01〜0.1% 0
- 0.1〜1% 0
- 1%以上 0
含有量の表示は多くが製品名に成分名を使った製品によるもので、名前だけの少量に偏っている可能性があります。
この成分を含む製品のうち85件は全成分の前の方(1%ラインより前)、171件は後ろ(ふつう1%以下)に書いています。
この成分を含む製品
確認済み 253件中 12件 · 十分に入っている製品から · 全 253件を見る
EASYDEWEASYDEW Topical MTS Shot Ampoule0.001%表示
Cos De BAHAES Serum0.0005%表示
EASYDEWDaewoong Pharmaceutical EASYDEW Dark Spot Ampoule 12ml0.00015%表示
RIREEGF Dipanthen Repair Eye Cream0.00001%表示
RIREEGF Peplink Eye Cream0.00001%表示
RIREEGF Midfit Lifting Ampoule0.00001%表示
RIREEGF Dipanthen Repair Cream0.00001%表示
RIREEGF Dipanthen Repair Cream0.00001%表示
SidmoolDual EGF Device Gel0.000005%表示
MEDIPEELMEDIPEEL EGF Scaling Moisture Foot Shampoo 200ml0.0000001%表示
TENZEROTENZERO Age Solution Ampoule0.00000001%表示
TENZEROTENZERO Age Solution Cream0.00000001%表示
定義
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids
化粧品での役割
注意が必要な場合があります
EGF is generally safe and well tolerated in topical formulations. It is suitable for all skin types, including sensitive and aging skin. Proper formulation ensures stability and bioavailability to maximize benefits without irritation.
使用の参考
EGF is a naturally occurring protein that binds to epidermal growth factor receptors (EGFR) on skin cells, initiating signaling cascades that stimulate cellular proliferation, migration, and differentiation. This accelerates epidermal turnover, promotes dermal fibroblast activation, and increases synthesis of collagen and elastin—key proteins for skin firmness, elasticity, and texture. EGF facilitates wound healing and tissue regeneration by promoting new cell growth and reducing scarring. It also improves skin hydration and barrier function, while reducing fine lines, wrinkles, hyperpigmentation, and skin sagging. EGF's ability to activate key growth pathways contributes to its effectiveness in rejuvenating aging skin and enhancing overall skin resilience.
安全性・規制情報
韓国
- 最大配合量 : 0.001%
出典: 韓国食薬処 化粧品規制情報
Other restriction: ban substances that deplete the ozone layer
出典: EU CosIng 成分リスト
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
公式表示名・定義
日本化粧品工業会の表示名称 合成ヒト遺伝子組換オリゴペプチド-1: 本品は、大腸菌 E. coli によって産生させた単鎖の合成ヒトペプチドである。出発遺伝子は、上皮成長因子のコードを持ち、宿主が使用できるようにしたヒト遺伝子の合成複製物であり、ジスルフィド結合と糖鎖付加の両方またはいずれか一方を含む最大で1207個のアミノ酸からなり、そのタンパク質は固有のアミノ酸配列を持つ。
出典: 日本化粧品工業会 表示名称
別名・識別情報
関連文献
- Therapy of secondary cutaneous toxicity as a result of radioterapic treatment, with a sH oligopeptide-1 cream based (epidermal growth factor-egf): a pilot study · 2018
- Topical application of sh-oligopeptide-1 and clinical trials with cosmetic preparations: risk or fraud? · 2023
- Update on the Research of an Emulgel for the Effective Treatment of Atopic Dermatitis: Clinical Investigation in Children · 2025
- Microencapsulation, Cream Development, and Controlled Clinical Study of an Upcycled Polyphenolic Extract Combined with sh-Oligopeptide-1 · 2024
- A pre-market interventional, single-arm clinical investigation of a new topical lotion based on hyaluronic acid and peptides, EGYFILTM, for the treatment of pain and stiffness in soft tissues · 2023