SH-OLIGOPEPTIDE-1

sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids

EGF is generally safe and well tolerated in topical formulations. It is suitable for all skin types, including sensitive and aging skin. Proper formulation ensures stability and bioavailability to maximize benefits without irritation.

EGF is a naturally occurring protein that binds to epidermal growth factor receptors (EGFR) on skin cells, initiating signaling cascades that stimulate cellular proliferation, migration, and differentiation. This accelerates epidermal turnover, promotes dermal fibroblast activation, and increases synthesis of collagen and elastin—key proteins for skin firmness, elasticity, and texture. EGF facilitates wound healing and tissue regeneration by promoting new cell growth and reducing scarring. It also improves skin hydration and barrier function, while reducing fine lines, wrinkles, hyperpigmentation, and skin sagging. EGF's ability to activate key growth pathways contributes to its effectiveness in rejuvenating aging skin and enhancing overall skin resilience.

South Korea

• Maximum concentration : 0.001%

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list