sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E.
- 韩国限量
- 0.001%
产品中实际含有多少
标示含量的产品 46 款中位数 0.000005%
- 低于 0.01% 46
- 0.01–0.1% 0
- 0.1–1% 0
- 1% 以上 0
标示含量的多为以该成分命名的产品,数值可能偏向象征性的少量添加。
含该成分的产品中,85 款将其列在 1% 线之前,171 款列在之后(通常不超过 1%)。
含有此成分的产品
已确认 253 款中的 12 款 · 按含量充足程度排序 · 查看全部 253 款
EASYDEWEASYDEW Topical MTS Shot Ampoule标示 0.001%
Cos De BAHAES Serum标示 0.0005%
EASYDEWDaewoong Pharmaceutical EASYDEW Dark Spot Ampoule 12ml标示 0.00015%
RIREEGF Dipanthen Repair Eye Cream标示 0.00001%
RIREEGF Peplink Eye Cream标示 0.00001%
RIREEGF Midfit Lifting Ampoule标示 0.00001%
RIREEGF Dipanthen Repair Cream标示 0.00001%
RIREEGF Dipanthen Repair Cream标示 0.00001%
SidmoolDual EGF Device Gel标示 0.000005%
MEDIPEELMEDIPEEL EGF Scaling Moisture Foot Shampoo 200ml标示 0.0000001%
TENZEROTENZERO Age Solution Ampoule标示 0.00000001%
TENZEROTENZERO Age Solution Cream标示 0.00000001%
定义
sh-Oligopeptide-1 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Epidermal Growth Factor. It contains a maximum of 53 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the standard amino acids
化妆品中的作用
可能需要注意
EGF is generally safe and well tolerated in topical formulations. It is suitable for all skin types, including sensitive and aging skin. Proper formulation ensures stability and bioavailability to maximize benefits without irritation.
使用参考
EGF is a naturally occurring protein that binds to epidermal growth factor receptors (EGFR) on skin cells, initiating signaling cascades that stimulate cellular proliferation, migration, and differentiation. This accelerates epidermal turnover, promotes dermal fibroblast activation, and increases synthesis of collagen and elastin—key proteins for skin firmness, elasticity, and texture. EGF facilitates wound healing and tissue regeneration by promoting new cell growth and reducing scarring. It also improves skin hydration and barrier function, while reducing fine lines, wrinkles, hyperpigmentation, and skin sagging. EGF's ability to activate key growth pathways contributes to its effectiveness in rejuvenating aging skin and enhancing overall skin resilience.
安全与法规参考
韩国
- 最大配合量 : 0.001%
来源: 韩国食药处 化妆品法规信息
Other restriction: ban substances that deplete the ozone layer
来源: 欧盟 CosIng 成分清单
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 合成ヒト遺伝子組換オリゴペプチド-1: 本品は、大腸菌 E. coli によって産生させた単鎖の合成ヒトペプチドである。出発遺伝子は、上皮成長因子のコードを持ち、宿主が使用できるようにしたヒト遺伝子の合成複製物であり、ジスルフィド結合と糖鎖付加の両方またはいずれか一方を含む最大で1207個のアミノ酸からなり、そのタンパク質は固有のアミノ酸配列を持つ。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
相关文献
- Therapy of secondary cutaneous toxicity as a result of radioterapic treatment, with a sH oligopeptide-1 cream based (epidermal growth factor-egf): a pilot study · 2018
- Topical application of sh-oligopeptide-1 and clinical trials with cosmetic preparations: risk or fraud? · 2023
- Update on the Research of an Emulgel for the Effective Treatment of Atopic Dermatitis: Clinical Investigation in Children · 2025
- Microencapsulation, Cream Development, and Controlled Clinical Study of an Upcycled Polyphenolic Extract Combined with sh-Oligopeptide-1 · 2024
- A pre-market interventional, single-arm clinical investigation of a new topical lotion based on hyaluronic acid and peptides, EGYFILTM, for the treatment of pain and stiffness in soft tissues · 2023