Definition
US FDA substance register · UNII BU8V88OWIQ · registered name Sodium bisulfate · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name 硫酸水素Ｎａ: 本品は、次の化学式で表される無機塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 7681-38-1
- EC No.EU chemical inventory number
- 231-665-7
- DTXSIDUS EPA chemical ID
- DTXSID3033983
- DTXCIDUS EPA compound ID
- DTXCID1013983
- IUPAC
- Sodium hydrogen sulfate
- Molecular formula
- HNaO4S
- Molecular weight
- 120.05 g/mol
Measured properties
- Appearance
- Bisulfate, aqueous solution is a white crystalline solid dissolved in water. It is corrosive to metals and tissue. · Other Solid, Dry Powder, Liquid
- Melting point
- Melting point equals 315 °C
- Density
- 2.43513 @25 °C
- pH
- Solutions are strongly acidic · 1
- Colour
- colourless
- Odour
- odourless
- Melting/freezing point
- 315 ℃()
- Initial boiling point and range
- 163.7~163.8 ℃
- Water solubility
- 285000 ㎎/ℓ(25℃, pH: 0.81)
- Vapour density
- 2.435
- Relative density
- 2.44
- Decomposition temperature
- 315 ℃
- Molecular weight
- 120.06
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 32 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- pH regulating agent10
- Processing aids not otherwise specified6
- Soil amendments2
- Bleaching agent2
- Solvent2
- Surfactant (surface active agent)2
- Food preservative (EPA)1
- Etching agent1
6 other uses
- Plating agent1
- Intermediate1
- Cleaning agent1
- Biocide1
- Sizing agent1
- Flavouring and nutrient1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 5 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Category 8.2C (Category 1C)
Skin Irritation · Read Across - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) adopted 12 May 1981 according to - Not classified
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Eye Dam. 1
Eye Irritation · Authoritative - Serious eye damage/eye irritation - Category 1
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) adopted 24 February 1987 according to - Category 2
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Plant pH level regulates the preference of hormone-treated Ceratapion basicorne (Coleoptera: Apionidae) for yellow starthistle. · 2026
- Protective effects of Andrographolide sodium bisulfate on UV-induced skin carcinogenesis in mice model. · 2022
- Broiler performance and litter ammonia levels as affected by sulfur added to the bird's diet · 2021
- Andrographolide sodium bisulfate attenuates UV-induced photo-damage by activating the keap1/Nrf2 pathway and downregulating the NF-κB pathway in HaCaT keratinocytes · 2019
- Andrographolide Sodium Bisulfate Prevents UV-Induced Skin Photoaging through Inhibiting Oxidative Stress and Inflammation · 2016
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese