Sodium butyrate is an organic sodium salt resulting from the replacement of the proton from the carboxy group of butyric acid by a sodium ion.
Definition
Sodium butyrate is an organic sodium salt resulting from the replacement of the proton from the carboxy group of butyric acid by a sodium ion. It has a role as a geroprotector and an EC 3.5.1.98 (histone deacetylase) inhibitor. It contains a butyrate.
Source: PubChem
US FDA substance register · UNII 8RAS91C36W · registered name Sodium butyrate · single chemical substance
Sodium Butyrate is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 156-54-7
- EC No.EU chemical inventory number
- 205-857-6
- DTXSIDUS EPA chemical ID
- DTXSID3037672
- DTXCIDUS EPA compound ID
- DTXCID1017672
- IUPAC
- Sodium butanoate
- Molecular formula
- C4H7NaO2
- Molecular weight
- 110.088 g/mol
Measured properties
- Appearance
- White powder, [MSDSonline]
- Density
- 0.96 @25 °C
- Melting/freezing point
- 250~253 ℃
- Water solubility
- (&, gt, 10%)
- Relative density
- 0.96 ()
- Molecular weight
- 110.09
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
Related literature
- Effects of Adding Encapsulated Sodium Butyrate and Arginine to Diets of Broiler Chickens Submitted to a Thermal Stress Model · 2025
- Pro-inflammatory regulation of EGFR-Annexin A2 synergy by sodium butyrate: An upstream target to reduce articular inflammation and cartilage destruction in rheumatoid arthritis. · 2025
- Anti-Inflammatory Effects of a Mixture of Lactic Acid Bacteria and Sodium Butyrate in Atopic Dermatitis Murine Model · 2018
- Abstract 2813: The synergistic anticancer activity of 1’-acetoxychavicol acetate and sodium butyrate in human hepatocellular carcinoma cells · 2016
- Combined treatment with sodium butyrate and PD153035 enhances keratinocyte differentiation · 2014
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese