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Ingredient Dictionary

SODIUM DEHYDROACETATE

Korean limit
0.6%
Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 48 list it before the 1% line and 360 after it (usually 1% or less).

Products using this ingredient

12 of 404 confirmed · likeliest to carry enough first · See all 404

Definition

US FDA substance register · UNII 8W46YN971G · registered name SODIUM DEHYDROACETATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Sodium Dehydroacetate is the heterocyclic compound that conforms generally to the formula:

Cosmetic roles

Stops microbes growing in the productPRESERVATIVE

Safety & regulatory references

Restricted
China · Japan · South Korea · Taiwan

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

  • Maximum concentration permitted at final product : 0.6% (expressed as acid)
  • Other limitations and requirements : Banned in sprayable systems (such as aerosols and sprays)

ASEAN

  • Maximum authorised concentration in the finished cosmetic product : 0.6% (acid)
  • Other limitations and requirements : Prohibited in aerosol dispensers (sprays)

European Union

  • Maximum concentration in ready for use preparation : 0.6% (as acid)
  • Other : Not to be used in aerosol dispensers (sprays)

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Restriction V/13

Source: EU CosIng ingredient list

Reviewed by CIR: Sodium Dehydroacetate and Dehydroacetic Acid

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Annual Review of Cosmetic Ingredient Safety Assessments - 2004/2005

Source: US Cosmetic Ingredient Review (CIR)

Reviewed by CIR: Final Report on the Safety Assessment of Sodium Dehydroacetate and Dehydroacetic Acid

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name デヒドロ酢酸Ｎａ: 本品は、デヒドロ酢酸（＊）のナトリウム塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

SODIUM DEHYDROACETATEINCI소듐데하이드로아세테이트Korean label name (MFDS standard)2H-Pyran-2,4(3H)-dione, 3-acetyl-6-methyl-, ion(1-), sodiumSynonymデヒドロ酢酸ＮａJapanese labelling name
CAS No.chemical registry number
4418-26-2
EC No.EU chemical inventory number
224-580-1
DTXSIDUS EPA chemical ID
DTXSID7026029
DTXCIDUS EPA compound ID
DTXCID501855011
IUPAC
Sodium 3-acetyl-6-methyl-2,4-dioxo-3,4-dihydro-2H-pyran-3-ide
Molecular formula
C8H7NaO4
Molecular weight
190.13 g/mol

Measured properties

Appearance
Sodium dehydroacetate is a white powder. Used as a fungicide, plasticizer, toothpaste, preservative in food. · Hydrate: White solid, [Hawley] White powder, [MSDSonline]
Solubility
Soluble (NTP, 1992) · INSOL IN MOST ORGANIC SOLVENTS /HYDRATE/
Colour
white
Melting/freezing point
280~285 ℃
Vapour pressure
(3.84E-012mmHg (25℃) est.)
Vapour density
6.6
Auto-ignition temperature
360 ℃
Molecular weight
190.14

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Preservative5
  • Dye1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 23 Jul 2010
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Classification not possible
    Skin Sensitization · Screening
  • Classification not possible
    Skin Irritation · Screening
  • Not classified
    Eye Irritation · Screening
  • Studies Indicate No Significant Irritation
    eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 438 (Isolated Chicken Eye Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) adopted Jul 2013 according to EU method B.48 (Isolated chicken eye test method for identifying occular corrosives and severe irritants) according to

Source: US EPA CompTox dashboard

Related literature

Linked databases 20

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