Definition
US FDA substance register · UNII 12838560LI · registered name SODIUM ETHASULFATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Report on the Safety Assessment of Sodium Cetearyl Sulfate and Related Alkyl Sulfates Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 126-92-1
- EC No.EU chemical inventory number
- 204-812-8
- DTXSIDUS EPA chemical ID
- DTXSID1026033
- DTXCIDUS EPA compound ID
- DTXCID706033
- IUPAC
- Sodium 2-ethylhexyl sulfate
- Molecular formula
- C8H17NaO4S
- Molecular weight
- 232.27 g/mol
Measured properties
- Appearance
- Sodium(2-ethylhexyl)alcohol sulfate is a clear, colorless, slightly viscous liquid. (NTP, 1992) · Liquid, Other Solid
- Boiling point
- 205 to 219 °F at 760 mmHg (NTP, 1992)
- Solubility
- greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
- Density
- 1.114 at 71.1 °F (NTP, 1992) - Denser than water, will sink
- Colour
- white
- Initial boiling point and range
- 191 ℃(calc., @1012 mBar)
- Vapour pressure
- 1.2 ㎩
- Water solubility
- 500 g/ℓ
- Vapour density
- 8.02
- Relative density
- 1.268 (@ 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- -0.248 (@ 25 ℃)
- Auto-ignition temperature
- 400 ℃
- Molecular weight
- 232.2743
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 23 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Cleaning agent8
- Surfactant (surface active agent)8
- Emulsifier3
- Dispersing agent1
- Solubility enhancer1
- Thickening agent1
- Wetting agent (non-aqueous)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to other guideline: patch-test technique described in the "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959), the US Association of Food and Drug Officials (AFDO) according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to other guideline: the test for eye irritants described in the "Appraisal of the Safety of Chemicals in Foods, Drugs and Cosmetics" (1959), the US Association of Food and Drug Offi-cials (AFDO) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata