Sodium dithionite is an inorganic sodium salt that is the disodium salt of dithionous acid.
Definition
US FDA substance register · UNII 2K5B8F6ES1 · registered name Sodium dithionite · single chemical substance
Sodium dithionite is an inorganic sodium salt that is the disodium salt of dithionous acid. It has a role as a bleaching agent and a reducing agent. It contains a dithionite(2-).
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Reviewed by CIR: Scientific Literature Review: Safety Assessment of Sodium Hydrosulfite as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 7631-94-9
- CAS No.chemical registry number
- 7775-14-6
- EC No.EU chemical inventory number
- 231-550-1
- EC No.EU chemical inventory number
- 231-890-0
- DTXSIDUS EPA chemical ID
- DTXSID9029697
- DTXCIDUS EPA compound ID
- DTXCID609697
- IUPAC
- Disodium dithionite
- Molecular formula
- Na2O4S2
- Molecular weight
- 174.1 g/mol
Measured properties
- Flash point
- &, gt, 100 ℃ (o.c.)
- Water solubility
- 25 g/100㎖
- Relative density
- 2.4
- n-Octanol/water partition coefficient (Kow)
- (&, lt, -4.7)
- Decomposition temperature
- (&, gt, 100 ℃)
- Molecular weight
- 174.10
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Reducing agent3
- Bleaching agent3
- pH regulating agent2
- Cleaning agent1
- Dye1
- Viscosity modifier1
- Processing aids not otherwise specified1
- Solvent1
1 other uses
- Chemical reaction regulator1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 5 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) , 2002-04-24 - Classification not possible
Skin Sensitization · Screening - Category 2
Skin Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) , adopted 2002-04-24 according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Category 2A-2B
Eye Irritation · Screening - Serious eye damage/eye irritation - Category 2B
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- METAL REDUCTION REACTIONS OF THE MELANINS: HISTOCHEMICAL STUDIES · 1957
- Degumming silk by CO2 supercritical fluid and their dyeing ability with plant indigo · 2020
- The Survey of Chemical Food Contaminant in Thailand University Games · 2010
- Determination of Pyoverdine, the Fluorescent Pigment of Pseudomonads, in Frozen Whole Egg · 1958
- Determination of pyoverdine, the fluorescent pigment of pseudomonads, in frozen whole egg. · 1958
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese