What is this ingredient?

미국 FDA 물질 등록 · UNII 3R36J71C17 · 등록명 SODIUM ISETHIONATE · 단일 화학물질

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Ingredient Dictionary

SODIUM ISETHIONATE

How much products actually contain

No product states its amount yet.

Of the products containing it, 81 list it before the 1% line and 83 after it (usually 1% or less).

Products using this ingredient

12 of 163 confirmed · likeliest to carry enough first · See all 163

Definition

US FDA substance register · UNII 3R36J71C17 · registered name SODIUM ISETHIONATE · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Reduces staticANTISTATICWashes away surface impuritiesCLEANSINGKeeps skin in good condition (CosIng catch-all)SKIN CONDITIONINGSoftens hairHAIR CONDITIONING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Reviewed by CIR: Amended Safety Assessment of Isethionate Salts as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name イセチオン酸Ｎａ: 本品は、イセチオン酸のナトリウム塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

SODIUM ISETHIONATEINCI소듐이세티오네이트Korean label name (MFDS standard)Ethanesulfonic acid, 2-hydroxy-, monosodium saltSynonymイセチオン酸ＮａJapanese labelling name

CAS No.chemical registry number: 1562-00-1
EC No.EU chemical inventory number: 216-343-6
DTXSIDUS EPA chemical ID: DTXSID7027413
DTXCIDUS EPA compound ID: DTXCID007413

IUPAC: Sodium 2-hydroxyethane-1-sulfonate
Molecular formula: C2H5NaO4S
Molecular weight: 148.11 g/mol

Measured properties

Appearance: solid
Melting/freezing point: 193~196 ℃
Initial boiling point and range: &amp, gt, 230 ℃
Water solubility: 650 ㎎/ℓ
n-Octanol/water partition coefficient (Kow): 3.38
Molecular weight: 148.114

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 45 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Surfactant (surface active agent)33
Softener and conditioner4
Cleaning agent2
Intermediate2
Anti-static agent2
Emulsifier1
No specific technical function1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low2

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to