What is this ingredient?

미국 FDA 물질 등록 · UNII CR6K9C2NHK · 등록명 Methylparaben Sodium · 단일 화학물질

All ingredients

Ingredient Dictionary

SODIUM METHYLPARABEN

How much products actually contain

No product states its amount yet.

Of the products containing it, 0 list it before the 1% line and 3 after it (usually 1% or less).

Products using this ingredient

3 of 3 confirmed · likeliest to carry enough first

Definition

US FDA substance register · UNII CR6K9C2NHK · registered name Methylparaben Sodium · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Stops microbes growing in the productPRESERVATIVE

Safety & regulatory references

Restricted: China · Japan · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

Maximum concentration permitted at final product : (a) 0,4% (expresso como ácido) para cada substância considerada em forma individual. (b) 0,8% (expresso como ácido) para a soma das concentrações individuais de ácido 4-p-hidroxibenzóico, seus ésteres de metil e etil e seus sais contidos no produto.
Other limitations and requirements : Prohibit: isopropylparaben, isobutylparaben, fenylparaben, benzylparaben, pentylparaben.

ASEAN

Maximum authorised concentration in the finished cosmetic product : 0.4% (as acid) for single ester 0.8% (as acid) for mixtures of esters

Taiwan

(a) 0.4%
(b) 0.8%

European Union

Maximum concentration in ready for use preparation : 0,4% (as acid) for single ester 0,8% (as acid) for mixtures of esters

Source: MFDS (Korea) cosmetic regulatory information

Restriction V/12

Source: EU CosIng ingredient list

Reviewed by CIR: Amended Safety Assessment of Parabens as Used in Cosmetics

Source: US Cosmetic Ingredient Review (CIR)

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name メチルパラベンＮａ: 本品は、メチルパラベン（＊）のナトリウム塩であり、次の化学式で表される。

Source: JCIA labelling names (Japan)

Names & identifiers

SODIUM METHYLPARABENINCI소듐메틸파라벤Korean label name (MFDS standard)Benzoic acid, 4-hydroxy-, methyl ester, sodium saltSynonymメチルパラベンＮａJapanese labelling name

CAS No.chemical registry number: 5026-62-0
EC No.EU chemical inventory number: 225-714-1
DTXSIDUS EPA chemical ID: DTXSID1042156
DTXCIDUS EPA compound ID: DTXCID9022156

IUPAC: Sodium 4-(methoxycarbonyl)phenolate
Molecular formula: C8H7NaO3
Molecular weight: 174.131 g/mol

Measured properties

Appearance: White, hygroscopic powder · solid
Melting point: The white precipitate formed by acidifying with hydrochloric acid a 10 % (w/v) aqueous solution of the sodium derivative of methylp-hydroxybenzoate (using litmus paper as indicator) shall, when washed with water and dried at 80 °C for two hours, have a melting range of 125 °C to 128 °C
pH: 9,7-10,3 (0,1 % solution in carbon dioxide free water)
Melting/freezing point: 313 ℃
Initial boiling point and range: 313 ℃
Flash point: 183 ℃(978mBar)
Vapour pressure: 8.55E-4 ㎜Hg (25℃)
Water solubility: 418 g/㎖ (20℃, pH11.4)
Vapour density: 6.041076976182257
Relative density: 1.42
n-Octanol/water partition coefficient (Kow): -0.63
Molecular weight: 175.01

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 6 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Preservative6

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

4 skin studies and 2 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 6 studies

Ambiguous
skin corrosion: in vitro / ex vivo · Screening · EU Method B.40 (In Vitro Skin Corrosion: Transcutaneous Electrical Resistance Test (TER)) according to other guideline: OECD Guideline 431 (In Vitro Skin Corrosion: Human Skin Model Test) according to
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Code of Federal Regulations, Title 16, Section 1500.41 according to
Category 6.3B (Category 3)
Skin Irritation · Read Across
Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Code of Federal Regulations, Title 16, Section 1500.42 according to
Category 6.4A (Category 2A)
Eye Irritation · Read Across