Ingredient Dictionary

SODIUM O-PHENYLPHENATE

o-Phenylphenate, Sodium can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).

Korean limit: 0.15%

SODIUM O-PHENYLPHENATE Molecular structure — Molecular structure

Definition

o-Phenylphenate, Sodium can cause cancer according to The World Health Organization's International Agency for Research on Cancer (IARC).

Source: PubChem

US FDA substance register · UNII KFV9K7N7UI · registered name Sodium O-Phenylphenate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Sodium o-Phenylphenate is the sodium salt of o-phenylphenol that conforms to the formula:

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Restricted: China · South Korea

Source: MFDS (Korea) cosmetic regulatory information

Argentina · Brazil

Maximum concentration permitted at final product : 0.2% (expressed as phenol)

Taiwan

0.2%

Japan

Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 0.15 g
Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 0.15 g

Source: MFDS (Korea) cosmetic regulatory information

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer · SCCS opinion: ADDENDUM to the scientific opinion on o-Phenylphenol, Sodium o-phenylphenate and Potassium o-phenylphenate (SCCS/1555/15)

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name フェニルフェノールＮａ: 本品は、フェニルフェノール（＊）のナトリウム塩である。

Source: JCIA labelling names (Japan)

JCIA labelling name ｏ－フェニルフェノールＮａ: 本品は、ｏ－フェニルフェノール（＊）のナトリウム塩である。

Source: JCIA labelling names (Japan)

Names & identifiers

SODIUM O-PHENYLPHENATEINCI[1,1'-Biphenyl]-2-ol, sodium saltSynonym소듐o-페닐페네이트Korean label name (MFDS standard)ｏ－フェニルフェノールＮａJapanese labelling nameフェニルフェノールＮａJapanese labelling name

CAS No.chemical registry number: 132-27-4
EC No.EU chemical inventory number: 205-055-6
DTXSIDUS EPA chemical ID: DTXSID2021153
DTXCIDUS EPA compound ID: DTXCID001153

IUPAC: Sodium [1,1'-biphenyl]-2-olate
Molecular formula: C12H9NaO
Molecular weight: 192.193 g/mol

Measured properties

Appearance: Sodium o-phenylphenoxide is a beige flaky solid. pH of saturated solution in water: 12.0-13.5. (NTP, 1992) · White solid, [Merck Index] Beige flaky solid, [CAMEO]
Solubility: greater than or equal to 100 mg/mL at 68 °F (NTP, 1992)
pH: 12.75
Melting/freezing point: 57 ℃
Evaporation rate: 1
Water solubility: 100 g/100㎖
Relative density: 1.3
n-Octanol/water partition coefficient (Kow): 0.59 (est.)

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 14 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Biocide7
Preservative5
Catalyst1
Defoamer1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

5 skin studies and 3 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 8 studies

Skin Irrit. 2
Skin Irritation · Authoritative
Category 6.5B (Category 1)
Skin Sensitization · Read Across
Category 1
Skin Irritation · Screening
Category 6.3A (Category 2)
Skin Irritation · Read Across
Not classified
Skin Sensitization · Screening
Category 8.3A (Category 1)
Eye Irritation · Read Across
Category 1
Eye Irritation · Screening
Eye Dam. 1
Eye Irritation · Authoritative