Definition
US FDA substance register · UNII OES0R93F0C · registered name SODIUM PANTOTHENATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Reviewed by CIR: Safety Assessment of Panthenol, Pantothenic Acid, and Derivatives as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name パントテン酸Ｎａ: 本品は、パントテン酸（＊）のナトリウム塩である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 867-81-2
- EC No.EU chemical inventory number
- 212-768-6
- DTXSIDUS EPA chemical ID
- DTXSID4047173
- DTXCIDUS EPA compound ID
- DTXCID2027173
- IUPAC
- Sodium N-[(2R)-2,4-dihydroxy-3,3-dimethylbutanoyl]-beta-alaninate
- Molecular formula
- C9H16NNaO5
- Molecular weight
- 241.219 g/mol
Measured properties
- Appearance
- Highly hygroscopic solid, [Merck Index] · (20°C, 1013 hPa)
- Melting point
- 171-178 °C
- Melting/freezing point
- &, lt, -75 ℃ (1 atm)
- Initial boiling point and range
- 215.5~250.5 ℃ (1 atm)
- Flash point
- 118 ℃(101325 Pa)
- Vapour pressure
- 0.11 hPa(20℃)
- Water solubility
- 34.5 ㎎/ℓ(20℃)
- Relative density
- 0.924
- n-Octanol/water partition coefficient (Kow)
- 4.3 (25℃)
- Auto-ignition temperature
- 220 ℃(101325 Pa)
- Molecular weight
- 180.29
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Softener and conditioner1
- Flavouring and nutrient1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 14
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata