SODIUM SALICYLATE
Sodium salicylate is an organic molecular entity.
製品には実際どれくらい入っているか
この成分の含有量を表示した製品はまだありません。
この成分を含む製品のうち6件は全成分の前の方(1%ラインより前)、67件は後ろ(ふつう1%以下)に書いています。
この成分を含む製品
確認済み 71件中 12件 · 十分に入っている製品から · 全 71件を見る
Labo HCooling & No-Sebum Shampoo 750ml
TRIMAYGreen Capsule Apple Vinegar Scalp Scaler
Labo HCooling & No-Sebum Shampoo 333ml Special Set (Hair Loss Relief Functional)
Labo HLabo H Cooling & No-Sebum Shampoo 750ml
COSRXCOSRX PEPTIDE-132 Ultra Perfect Hair Bonding Shampoo
ColourPopColourPop The Daily Face Cream
ILLIYOONFresh Moisture Scrub Wash (Monchhichi Limited Edition)
NativeNative Body Wash - Last Chance
NativeNative Body Wash
NativeNative Daily Clean Shampoo
NativeNative Daily Clean Shampoo - Last Chance
NativeNative Full & Thick Shampoo
定義
米国FDA 物質登録 · UNII WIQ1H85SYP · 登録名 Sodium Salicylate · 単一の化学物質
Sodium Salicylate is the sodium salt of salicylic acid that conforms to the formula:
Sodium salicylate is an organic molecular entity.
出典: PubChem
化粧品での役割
安全性・規制情報
- 制限
- 韓国 · 中国
出典: 韓国食薬処 化粧品規制情報
アルゼンチン · ブラジル
- Maximum concentration permitted at final product : 0.5% (expressed as acid)
- Other limitations and requirements : Prohibited in products for children under 3 years of age, except for shampoos.
- Use conditions and warnings that must appear on the label : Products for use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age (except shampoo)"
ASEAN
- Field of application and/or use : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
- Maximum authorised concentration in the finished cosmetic product : (a) 3.0 % (b) 2.0% (c) 0.5%
- Other limitations and requirements : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid. As a preservative, see Annex VI, Part 1, No 3
- Conditions of use and warning which must be printed on the labels : (a) (b) (c) Not to be used for children under three years of age
- Solely for products which might be used for children
- Maximum authorised concentration in the finished cosmetic product : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other limitations and requirements : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
- Conditions of use and warning which must be printed on the labels : Salicylic acid: Not to be used for children under 3 years of age Salicylic acid salts: Not to be used for children under 3 years of age
台湾
- 倘前述三國家地區政府管理有差異時,則採其中限量規定方式最安全者。
- ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
- 用途 : 防腐
日本
- 100gあたりの最大配合量(Maximum amount of ingredient per 100 g) : 1.0 as total(合計量として1.0)
欧州連合
- Maximum concentration in ready for use preparation : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other : Not to be used in products for children under 3 years of age, except for shampoos
- Wording of conditions of use and warnings : Salicylic acid: Not to be used for children under 3 years of age **Solely for products which might be used for children under 3 years of age. Salicylic acid salts: Not to be used for children under 3 years of age ***Solely for products which might be used for children under 3 years of age and which remain in prolonged contact with the skin.
出典: 韓国食薬処 化粧品規制情報
韓国の有害物質GHS分類なし · 既存化学物質
Restriction V/3 · SCCS opinion: Opinion concerning Salicylic Acid; OPINION ON salicylic acid (CAS 69-72-7) Submission I
出典: EU CosIng 成分リスト
Reviewed by CIR: Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
出典: 米国CIR 安全性評価
Reviewed by CIR: Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate
出典: 米国CIR 安全性評価
詳しい資料 — 表示名・識別番号・物性・試験記録・文献
公式表示名・定義
日本化粧品工業会の表示名称 サリチル酸Na: 本品は、サリチル酸(*)のナトリウム塩であり、次の化学式で表される。
出典: 日本化粧品工業会 表示名称
別名・識別情報
- CAS No.化学物質登録番号
- 54-21-7
- EC No.EU化学物質目録番号
- 200-198-0
- DTXSID米国EPA化学物質番号
- DTXSID5021708
- DTXCID米国EPA化合物番号
- DTXCID701708
- IUPAC
- Sodium 2-hydroxybenzoate
- 分子式
- C7H5NaO3
- 分子量
- 160.104 g/mol
測定された物性
- 性状
- Dry Powder · 固体
- 色
- 白色
- pH
- 6.21 (@ 27 ℃, 1 %)
- 蒸気圧
- 0.0000000000368 ㎜Hg (@ 25 ℃, 推定値)
- 溶解度
- 125000 ㎎/ℓ (@ 25 ℃)
- 蒸気密度
- 5.53
- 比重
- 0.56 (@ 25 ℃)
- n-オクタノール/水分配係数(Kow)
- -1.43
- 分解温度
- 213 ℃
- 分子量
- 160.10
物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。
出典: PubChem · 韓国安全保健公団 SDS
製品が実際に使っている用途
刺激・感作試験の記録
皮膚試験5件・眼試験9件の記録があります。
試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。
試験14件をすべて見る
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Patch test - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below - Category 6.3B (Category 3)
Skin Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Draize method according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Draize test according to - Severe Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: The Vitrigel-EIT method according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Serious eye damage/eye irritation - Category 2B
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: Short time exposure (STE) test according to
出典: 米国EPA CompTox
関連文献
- Modification of diffusion rates of benzocaine from topical vehicles using sodium salicylate as complexing agent. · 1976
- Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Para-Amino Benzoic Acid · 2016
- A randomised controlled trial of subcutaneous sodium salicylate therapy for osteoarthritis of the thumb · 2010
- The treatment of lateral epicondylitis by iontophoresis of sodium salicylate and sodium diclofenac · 1998
- Influence of dimethyl sulfoxide (DMSO) on the percutaneous absorption of salicylic acid and sodium salicylate from ointments. · 1968
連携データベース 20
- ChEBI
- EU CosIng 成分リスト 2
- PubChem 2
- Tlooto 学術文献検索 2 3 4 5
- UniChem 化学物質統合ID
- Wikidata
- Wikipedia · 英語 · 日本語 · 中国語
- オーストラリア 化学物質リスト(AICIS)
- 韓国 有害物質GHS情報(環境公団)
- 韓国安全保健公団 SDS
- 韓国食薬処 化粧品規制情報 2 3
- 韓国食薬処 化粧品原料成分 2
- 大韓化粧品協会 成分辞典
- 中国 既存化粧品原料リスト(IECIC)
- 日本化粧品工業会 表示名称
- 米国CIR 安全性評価 2 3
- 米国EPA CompTox 2
- 米国EPA 化学物質DB(DSSTox)
- 米国FDA 物質識別番号(UNII)
- 米国FDA 物質登録(GSRS)