Sodium salicylate is an organic molecular entity.
How much products actually contain
No product states its amount yet.
Of the products containing it, 6 list it before the 1% line and 67 after it (usually 1% or less).
Products using this ingredient
12 of 71 confirmed · likeliest to carry enough first · See all 71
Labo HCooling & No-Sebum Shampoo 750ml
TRIMAYGreen Capsule Apple Vinegar Scalp Scaler
Labo HCooling & No-Sebum Shampoo 333ml Special Set (Hair Loss Relief Functional)
Labo HLabo H Cooling & No-Sebum Shampoo 750ml
COSRXCOSRX PEPTIDE-132 Ultra Perfect Hair Bonding Shampoo
ColourPopColourPop The Daily Face Cream
ILLIYOONFresh Moisture Scrub Wash (Monchhichi Limited Edition)
NativeNative Body Wash - Last Chance
NativeNative Body Wash
NativeNative Daily Clean Shampoo
NativeNative Daily Clean Shampoo - Last Chance
NativeNative Full & Thick Shampoo
Definition
US FDA substance register · UNII WIQ1H85SYP · registered name Sodium Salicylate · single chemical substance
Sodium Salicylate is the sodium salt of salicylic acid that conforms to the formula:
Sodium salicylate is an organic molecular entity.
Source: PubChem
Cosmetic roles
Safety & regulatory references
- Restricted
- China · Japan · South Korea · Taiwan
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Maximum concentration permitted at final product : 0.5% (expressed as acid)
- Other limitations and requirements : Prohibited in products for children under 3 years of age, except for shampoos.
- Use conditions and warnings that must appear on the label : Products for use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age (except shampoo)"
ASEAN
- Field of application and/or use : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
- Maximum authorised concentration in the finished cosmetic product : (a) 3.0 % (b) 2.0% (c) 0.5%
- Other limitations and requirements : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid. As a preservative, see Annex VI, Part 1, No 3
- Conditions of use and warning which must be printed on the labels : (a) (b) (c) Not to be used for children under three years of age
- Solely for products which might be used for children
- Maximum authorised concentration in the finished cosmetic product : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other limitations and requirements : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
- Conditions of use and warning which must be printed on the labels : Salicylic acid: Not to be used for children under 3 years of age Salicylic acid salts: Not to be used for children under 3 years of age
European Union
- Maximum concentration in ready for use preparation : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other : Not to be used in products for children under 3 years of age, except for shampoos
- Wording of conditions of use and warnings : Salicylic acid: Not to be used for children under 3 years of age **Solely for products which might be used for children under 3 years of age. Salicylic acid salts: Not to be used for children under 3 years of age ***Solely for products which might be used for children under 3 years of age and which remain in prolonged contact with the skin.
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction V/3 · SCCS opinion: Opinion concerning Salicylic Acid; OPINION ON salicylic acid (CAS 69-72-7) Submission I
Source: EU CosIng ingredient list
Reviewed by CIR: Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
Reviewed by CIR: Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name サリチル酸Ｎａ: 本品は、サリチル酸（＊）のナトリウム塩であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 54-21-7
- EC No.EU chemical inventory number
- 200-198-0
- DTXSIDUS EPA chemical ID
- DTXSID5021708
- DTXCIDUS EPA compound ID
- DTXCID701708
- IUPAC
- Sodium 2-hydroxybenzoate
- Molecular formula
- C7H5NaO3
- Molecular weight
- 160.104 g/mol
Measured properties
- Appearance
- Dry Powder · solid
- Colour
- white
- pH
- 6.21 (@ 27 ℃, 1 %)
- Vapour pressure
- 0.0000000000368 ㎜Hg (@ 25 ℃, est.)
- Water solubility
- 125000 ㎎/ℓ (@ 25 ℃)
- Vapour density
- 5.53
- Relative density
- 0.56 (@ 25 ℃)
- n-Octanol/water partition coefficient (Kow)
- -1.43
- Decomposition temperature
- 213 ℃
- Molecular weight
- 160.10
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Preservative5
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 9 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 14 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Patch test - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below - Category 6.3B (Category 3)
Skin Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Draize method according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Draize test according to - Severe Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: The Vitrigel-EIT method according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Serious eye damage/eye irritation - Category 2B
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: Short time exposure (STE) test according to
Source: US EPA CompTox dashboard
Related literature
- Modification of diffusion rates of benzocaine from topical vehicles using sodium salicylate as complexing agent. · 1976
- Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Para-Amino Benzoic Acid · 2016
- A randomised controlled trial of subcutaneous sodium salicylate therapy for osteoarthritis of the thumb · 2010
- The treatment of lateral epicondylitis by iontophoresis of sodium salicylate and sodium diclofenac · 1998
- Influence of dimethyl sulfoxide (DMSO) on the percutaneous absorption of salicylic acid and sodium salicylate from ointments. · 1968
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese