Gloshell
成分辞典

成分辞典

サリチル酸Na

SODIUM SALICYLATE

Sodium salicylate is an organic molecular entity.

分子構造

製品には実際どれくらい入っているか

この成分の含有量を表示した製品はまだありません。

この成分を含む製品のうち6件は全成分の前の方(1%ラインより前)、67件は後ろ(ふつう1%以下)に書いています。

この成分を含む製品

確認済み 71件中 12件 · 十分に入っている製品から · 全 71件を見る

定義

米国FDA 物質登録 · UNII WIQ1H85SYP · 登録名 Sodium Salicylate · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

Sodium Salicylate is the sodium salt of salicylic acid that conforms to the formula:

Sodium salicylate is an organic molecular entity.

出典: PubChem

化粧品での役割

アルコールを飲用不可にするDENATURANT製品中の微生物の増殖を防ぐPRESERVATIVE

安全性・規制情報

制限
韓国 · 中国

出典: 韓国食薬処 化粧品規制情報

アルゼンチン · ブラジル

  • Maximum concentration permitted at final product : 0.5% (expressed as acid)
  • Other limitations and requirements : Prohibited in products for children under 3 years of age, except for shampoos.
  • Use conditions and warnings that must appear on the label : Products for use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age (except shampoo)"

ASEAN

  • Field of application and/or use : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
  • Maximum authorised concentration in the finished cosmetic product : (a) 3.0 % (b) 2.0% (c) 0.5%
  • Other limitations and requirements : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid. As a preservative, see Annex VI, Part 1, No 3
  • Conditions of use and warning which must be printed on the labels : (a) (b) (c) Not to be used for children under three years of age
  • Solely for products which might be used for children
  • Maximum authorised concentration in the finished cosmetic product : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
  • Other limitations and requirements : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
  • Conditions of use and warning which must be printed on the labels : Salicylic acid: Not to be used for children under 3 years of age Salicylic acid salts: Not to be used for children under 3 years of age

台湾

  • 倘前述三國家地區政府管理有差異時,則採其中限量規定方式最安全者。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • 用途 : 防腐

日本

  • 100gあたりの最大配合量(Maximum amount of ingredient per 100 g) : 1.0 as total(合計量として1.0)

欧州連合

  • Maximum concentration in ready for use preparation : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
  • Other : Not to be used in products for children under 3 years of age, except for shampoos
  • Wording of conditions of use and warnings : Salicylic acid: Not to be used for children under 3 years of age **Solely for products which might be used for children under 3 years of age. Salicylic acid salts: Not to be used for children under 3 years of age ***Solely for products which might be used for children under 3 years of age and which remain in prolonged contact with the skin.

出典: 韓国食薬処 化粧品規制情報

韓国の有害物質GHS分類なし · 既存化学物質

出典: 韓国 有害物質GHS情報(環境公団)

Restriction V/3 · SCCS opinion: Opinion concerning Salicylic Acid; OPINION ON salicylic acid (CAS 69-72-7) Submission I

出典: EU CosIng 成分リスト

Reviewed by CIR: Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

公式表示名・定義

日本化粧品工業会の表示名称 サリチル酸Na: 本品は、サリチル酸(*)のナトリウム塩であり、次の化学式で表される。

出典: 日本化粧品工業会 表示名称

別名・識別情報

SODIUM SALICYLATEINCI소듐살리실레이트韓国の表示名(食薬処標準名)Benzoic acid, 2-hydroxy-, sodium salt (1:1)別名サリチル酸Na日本の表示名称
CAS No.化学物質登録番号
54-21-7
EC No.EU化学物質目録番号
200-198-0
DTXSID米国EPA化学物質番号
DTXSID5021708
DTXCID米国EPA化合物番号
DTXCID701708
IUPAC
Sodium 2-hydroxybenzoate
分子式
C7H5NaO3
分子量
160.104 g/mol

測定された物性

性状
Dry Powder · 固体
色
白色
pH
6.21 (@ 27 ℃, 1 %)
蒸気圧
0.0000000000368 ㎜Hg (@ 25 ℃, 推定値)
溶解度
125000 ㎎/ℓ (@ 25 ℃)
蒸気密度
5.53
比重
0.56 (@ 25 ℃)
n-オクタノール/水分配係数(Kow)
-1.43
分解温度
213 ℃
分子量
160.10

物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: PubChem · 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品5件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Preservative5

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験5件・眼試験9件の記録があります。

低いと分類6件

試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験14件をすべて見る
  • Not likely to be sensitizing
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Studies Indicate No Significant Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • Not likely to be sensitizing
    skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Patch test
  • Not likely to be sensitizing
    skin sensitisation · Screening · according to other guideline: as mentioned below
  • Category 6.3B (Category 3)
    Skin Irritation · Read Across
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to
  • Severe Irritation
    eye irritation: in vivo · Screening · other guideline: as mentioned below according to
  • Studies Indicate No Significant Irritation
    eye irritation: in vivo · Screening · other guideline: Draize method according to
  • Severe Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vivo · Screening · other guideline: Draize test according to
  • Severe Irritation
    eye irritation: in vitro / ex vivo · Screening · other guideline: The Vitrigel-EIT method according to
  • Category 6.4A (Category 2A)
    Eye Irritation · Read Across
  • Serious eye damage/eye irritation - Category 2B
    Eye Irritation · Screening
  • Corrosive or Irritation Persists for > 21 days
    eye irritation: in vitro / ex vivo · Screening · other guideline: Short time exposure (STE) test according to

出典: 米国EPA CompTox

関連文献

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