Sodium salicylate is an organic molecular entity.
产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中,6 款将其列在 1% 线之前,67 款列在之后(通常不超过 1%)。
含有此成分的产品
已确认 71 款中的 12 款 · 按含量充足程度排序 · 查看全部 71 款
Labo HCooling & No-Sebum Shampoo 750ml
TRIMAYGreen Capsule Apple Vinegar Scalp Scaler
Labo HCooling & No-Sebum Shampoo 333ml Special Set (Hair Loss Relief Functional)
Labo HLabo H Cooling & No-Sebum Shampoo 750ml
COSRXCOSRX PEPTIDE-132 Ultra Perfect Hair Bonding Shampoo
ColourPopColourPop The Daily Face Cream
ILLIYOONFresh Moisture Scrub Wash (Monchhichi Limited Edition)
NativeNative Body Wash - Last Chance
NativeNative Body Wash
NativeNative Daily Clean Shampoo
NativeNative Daily Clean Shampoo - Last Chance
NativeNative Full & Thick Shampoo
定义
美国FDA 物质登记 · UNII WIQ1H85SYP · 登记名称 Sodium Salicylate · 单一化学物质
Sodium Salicylate is the sodium salt of salicylic acid that conforms to the formula:
Sodium salicylate is an organic molecular entity.
来源: PubChem
化妆品中的作用
安全与法规参考
- 限用
- 韩国 · 中国
来源: 韩国食药处 化妆品法规信息
阿根廷 · 巴西
- Maximum concentration permitted at final product : 0.5% (expressed as acid)
- Other limitations and requirements : Prohibited in products for children under 3 years of age, except for shampoos.
- Use conditions and warnings that must appear on the label : Products for use Adults: "Do not use in children" For products aimed at children: "Do not use in children under three years of age (except shampoo)"
东盟
- Field of application and/or use : (a) Rinse-off hair products (b) Other products except body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant (c) Body lotion, eye shadow, mascara, eyeliner, lipstick, roll-on deodorant
- Maximum authorised concentration in the finished cosmetic product : (a) 3.0 % (b) 2.0% (c) 0.5%
- Other limitations and requirements : (a) (b) (c) Not to be used in preparations for children under 3 years of age. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Not to be used in oral products. For purposes other than inhibiting the development of micro-organisms in the product. This purpose has to be apparent from the presentation of the product. These levels are inclusive of any use of salicylic acid. As a preservative, see Annex VI, Part 1, No 3
- Conditions of use and warning which must be printed on the labels : (a) (b) (c) Not to be used for children under three years of age
- Solely for products which might be used for children
- Maximum authorised concentration in the finished cosmetic product : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other limitations and requirements : Salicylic acid: Not to be used in products for children under 3 years of age. Not to be used in oral products. Not to be used in applications that may lead to exposure of the end-user’s lungs by inhalation. Salicylic acid salts: Not to be used in products for children under 3 years of age, except for shampoos.
- Conditions of use and warning which must be printed on the labels : Salicylic acid: Not to be used for children under 3 years of age Salicylic acid salts: Not to be used for children under 3 years of age
台湾
- 倘前述三國家地區政府管理有差異時,則採其中限量規定方式最安全者。
- ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
- 用途 : 防腐
日本
- 每100g最大配合量(Maximum amount of ingredient per 100 g) : 1.0 as total(合計量として1.0)
欧盟
- Maximum concentration in ready for use preparation : Salicylic acid: 0,5 % (acid) Salicylic acid salts: 0,5 % (acid)
- Other : Not to be used in products for children under 3 years of age, except for shampoos
- Wording of conditions of use and warnings : Salicylic acid: Not to be used for children under 3 years of age **Solely for products which might be used for children under 3 years of age. Salicylic acid salts: Not to be used for children under 3 years of age ***Solely for products which might be used for children under 3 years of age and which remain in prolonged contact with the skin.
来源: 韩国食药处 化妆品法规信息
未列入韩国有毒物质 GHS 分类 · 现有化学物质
Restriction V/3 · SCCS opinion: Opinion concerning Salicylic Acid; OPINION ON salicylic acid (CAS 69-72-7) Submission I
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Amended Safety Assessment of Salicylic Acid and Salicylates as Used in Cosmetics
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Report on the Safety Assessment of Salicylic Acid, Butyloctyl Salicylate, Calcium Salicylate, C12-15 Alkyl Salicylate, Capryloyl Salicylic Acid, Hexyldodecyl Salicylate, Isocetyl Salicylate, Isodecyl Salicylate, Magnesium Salicylate, MEA-Salicylate, Ethylhexyl Salicylate, Potassium Salicylate, Methyl Salicylate, Myristyl Salicylate, Sodium Salicylate, TEA-Salicylate, and Tridecyl Salicylate
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 サリチル酸Na: 本品は、サリチル酸(*)のナトリウム塩であり、次の化学式で表される。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 54-21-7
- EC No.欧盟化学品目录编号
- 200-198-0
- DTXSID美国EPA化学品编号
- DTXSID5021708
- DTXCID美国EPA化合物编号
- DTXCID701708
- IUPAC
- Sodium 2-hydroxybenzoate
- 分子式
- C7H5NaO3
- 分子量
- 160.104 g/mol
实测物性
- 性状
- Dry Powder · 固体
- 颜色
- 白色
- pH
- 6.21 (@ 27 ℃, 1 %)
- 蒸气压
- 0.0000000000368 ㎜Hg (@ 25 ℃, 估算值)
- 溶解度
- 125000 ㎎/ℓ (@ 25 ℃)
- 蒸气密度
- 5.53
- 比重
- 0.56 (@ 25 ℃)
- 正辛醇/水分配系数(Kow)
- -1.43
- 分解温度
- 213 ℃
- 分子量
- 160.10
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: PubChem · 韩国安全保健公团 安全数据表
产品实际使用的用途
刺激与致敏试验记录
记录有皮肤试验 5 项、眼部试验 9 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 14 项试验
- Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Patch test - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: as mentioned below - Category 6.3B (Category 3)
Skin Irritation · Read Across - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 492 (Reconstructed Human Cornea-like Epithelium (RhCE) Test Method for Identifying Chemicals Not Requiring Classification and Labelling for Eye Irritation or Serious Eye Damage) according to - Severe Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Draize method according to - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · other guideline: Draize test according to - Severe Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: The Vitrigel-EIT method according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Serious eye damage/eye irritation - Category 2B
Eye Irritation · Screening - Corrosive or Irritation Persists for > 21 days
eye irritation: in vitro / ex vivo · Screening · other guideline: Short time exposure (STE) test according to
来源: 美国EPA CompTox
相关文献
- Modification of diffusion rates of benzocaine from topical vehicles using sodium salicylate as complexing agent. · 1976
- Spectrophotometric Determination of Sodium Salicylate in Pharmaceutical Preparations by Coupling with Diazotized Para-Amino Benzoic Acid · 2016
- A randomised controlled trial of subcutaneous sodium salicylate therapy for osteoarthritis of the thumb · 2010
- The treatment of lateral epicondylitis by iontophoresis of sodium salicylate and sodium diclofenac · 1998
- Influence of dimethyl sulfoxide (DMSO) on the percutaneous absorption of salicylic acid and sodium salicylate from ointments. · 1968
关联数据库 20
- 澳大利亚工业化学品名录(AICIS)
- 韩国安全保健公团 安全数据表
- 韩国化妆品协会成分词典
- 韩国食药处 化妆品法规信息 2 3
- 韩国食药处 化妆品原料成分 2
- 韩国有毒物质 GHS 信息(环境公团)
- 美国CIR 安全性评估 2 3
- 美国EPA 化学品数据库(DSSTox)
- 美国EPA CompTox 2
- 美国FDA 物质登记(GSRS)
- 美国FDA 物质识别码(UNII)
- 欧盟 CosIng 成分清单 2
- 日本化妆品工业联合会标示名称
- 中国已使用化妆品原料目录(IECIC)
- ChEBI
- PubChem 2
- Tlooto 学术文献检索 2 3 4 5
- UniChem 化学物质统一 ID
- Wikidata
- Wikipedia · 英语 · 日语 · 中文