Definition
US FDA substance register · UNII YGR27ZW0Y7 · registered name Sodium sulfide anhydrous · single chemical substance
Cosmetic roles
Safety & regulatory references
- Restricted or banned
- China · South Korea
Source: MFDS (Korea) cosmetic regulatory information
Argentina · Brazil
- Field of application and/or use : (a) (b) and Depilatories
- Maximum concentration permitted at final product : a.- 2% calculated as sulfur pH up to 12.7 b.- 6% calculated as sulfur pH to 12.7
- Use conditions and warnings that must appear on the label : a.- b.- and Keep out of the reach of children. Avoid contact with eyes.
ASEAN
- Field of application and/or use : (a) Depilatories (b) Depilatories
- Maximum authorised concentration in the finished cosmetic product : (a) 2% calculated as sulphur pH up to 12.7 (b) 6% calculated as sulphur pH up to 12.7
- Conditions of use and warning which must be printed on the labels : (a) • Keep out of reach of children • Avoid contact with eyes (b) • Keep out of reach of children • Avoid contact with eyes
Canada
- Conditions of Use by product type : In hair removal (depilatory) products
- Maximum Concentration Permitted : 2% as sulfur
European Union
- Product Type, body parts : (a) Depilatories (b) Depilatories
- Maximum concentration in ready for use preparation : (a) 2% (as sulphur) (b) 6% (as sulphur)
- Other : pH<=12.7
- Wording of conditions of use and warnings : (a) (b) Keep out of reach of children Avoid contact with eyes
Source: MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Restriction III/23 · Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 1313-82-2
- EC No.EU chemical inventory number
- 215-211-5
- DTXSIDUS EPA chemical ID
- DTXSID0029636
- DTXCIDUS EPA compound ID
- DTXCID601030496
- IUPAC
- Disodium sulfide
- Molecular formula
- Na2S
- Molecular weight
- 78.04 g/mol
Measured properties
- Appearance
- Sodium sulfide, hydrated, with not less than 30% water appears as yellow-pink or white deliquescent crystals, flakes or lumps. Contains at least 30% water. Alkaline. Burns skin, eyes and mucous membranes. Mildly corrosive to most metals. May be toxic by skin absorption. Releases toxic hydrogen sulfide gas when mixed with an acid. · Wet Solid, Other Solid, Dry Powder, CBI, Large Crystals, Liquid
- Vapour pressure
- (4.59E-17mmHg @ 25℃ (est.))
- Water solubility
- 18.6 g/100㎖ (20℃)
- Relative density
- 1.856 (14℃)
- n-Octanol/water partition coefficient (Kow)
- -3.5
- Auto-ignition temperature
- (&, gt, 480℃)
- Decomposition temperature
- 920 ℃
- Molecular weight
- 78.04
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 15 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified4
- Intermediate3
- Solids separation (precipitating) agent, not other2
- Depilatory (EPA)1
- Reducing agent1
- Cleaning agent1
- Lubricating agent1
- Tanning agents not otherwise specified1
1 other uses
- Density modifier1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Classification not possible
Skin Sensitization · Screening - Skin Corr. 1B
Skin Irritation · Authoritative - Category 8.2B (Category 1B)
Skin Irritation · Read Across - Category 1A-1C
Skin Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- Anti-inflammatory effect of hydrogen sulfide donor sodium-sulfide in an experimental mouse model of contact hypersensitivity · 2023
- The Effect of Different Preoperative Depilation Ways on the Healing of Wounded Skin in Mice · 2022
- Latex peptidases of Calotropis procera for dehairing of leather as an alternative to environmentally toxic sodium sulfide treatment · 2017
- Impaired hydrogen sulfide-mediated vasodilation contributes to microvascular endothelial dysfunction in hypertensive adults · 2017
- Development of an Alternative Enzyme-assisted Dehairing Method of Animal Skins using Proteases from Bacillus licheniformis MZK05M9 · 2016
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese