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SODIUM THIOGLYCOLATE

Sodium thioglycolate is an organic sodium salt having thioglycolate(1) as the counterion.

Estructura molecular

Definición

Sodium thioglycolate is an organic sodium salt having thioglycolate(1) as the counterion. It has a role as a reducing agent. It contains a thioglycolate(1-).

Fuente: PubChem

Registro de sustancias de la FDA (EE. UU.) · UNII D94M78P69V · nombre registrado SODIUM THIOGLYCOLATE · sustancia química única

Fuente: Identificador único de ingredientes de la FDA (UNII)

Funciones cosméticas

Riza o alisa el cabelloHAIR WAVING OR STRAIGHTENINGRetrasa el deterioro por oxidaciónANTIOXIDANTDisuelve el vello para eliminarloDEPILATORYReduce otros ingredientesREDUCING

Referencias de seguridad y regulación

Restringido
Corea del Sur

Fuente: Información regulatoria cosmética del MFDS (Corea)

Argentina · Brasil

  • Field of application and/or use : (a) Products for hair straightening or waving: 1. General use 2. Professional use (b) Depilatories (c) Other products for hair care which are removed after application
  • Maximum concentration permitted at final product : (a) 1. 8% ready to use pH 7 to 9.5 2. 11% ready to use pH 7 to 9.5 (b) 5% ready to use pH 7 to 12.7 (c) 2% .ready to use pH 7 to 9.5 The indicated percentages are calculated as thioglycolic acid
  • Other limitations and requirements : a, b and c) In the USAGE must obligatorily the following information recorded: - Avoid contact with eyes. - In case of contact with eyes, rinse immediately with plenty water and consult a doctor - and c) Wear suitable gloves
  • Use conditions and warnings that must appear on the label : a), b) and c) - Contains thioglycolic acid salts - Follow instructions - Keep out of reach of children - Only for professional use (where appropriate)

ASEAN

  • Field of application and/or use : (a) Hair waving or straightening products: 1. General use 2. Professional use (b) Depilatories (c) Other hair care products which are removed after application
  • Maximum authorised concentration in the finished cosmetic product : (a) 1. 8% ready for use at pH 7 – 9.5 2. 11% ready for use at pH 7- 9.5 (b) 5% ready for use at pH 7-12.7 (c) 2% ready for use at pH 7-9.5 For general use of hair waving or straightening products the maximum concentration for combination of Thioglycolic acid and thiolactic acid must not exceed 8% calculated as Thioglycolic Acid.
  • Other limitations and requirements : (a) (b) (c) The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • Avoid contact with eyes • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves (a) and (c) only.
  • Conditions of use and warning which must be printed on the labels : (a) • Contains thioglycolate • Follow the instructions • Keep out of reach of children. • For professional use only. (b) and (c) • Contains thioglycolate • Follow the instructions • Keep out of reach of children

Canadá

  • Conditions of Use by product type : (a) Eyelash curling products (b) Hair dyes, waving or straightening products (c) Hair dyes, waving or straightening products for professional use (d) Depilatory products
  • Maximum Concentration Permitted : ((a) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (b) 8% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (c) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (d) 5% (as thioglycolic aci(d) with a pH less than or equal to 12.7
  • Warnings and Cautionary Statements: (to the effect of) : (a) "For professional use only.", "Avoid direct skin contact, wear suitable gloves.", "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention." (b)"Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." (c) "For professional use only." "Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." d) "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention."

China

  • Concentración máxima : (a)

Unión Europea

  • Product Type, body parts : (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
  • Maximum concentration in ready for use preparation : (a) 1) 8% 2) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
  • Other : (a) General use ready for use pH 7 to 9.5 Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5
  • Wording of conditions of use and warnings : Condition of use: (a) (b) (c) Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a) (d) For professional use only: Cotains thiglycolata, folow the instruction.

Fuente: Información regulatoria cosmética del MFDS (Corea)

Sin clasificación en la lista GHS de sustancias tóxicas de Corea · sustancia química existente

Fuente: Registro GHS de sustancias tóxicas de Corea (NIER)

Restriction III/2a · Other restriction: ban substances that deplete the ozone layer

Fuente: Lista de ingredientes CosIng (UE)

Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

Fuente: Cosmetic Ingredient Review (CIR, EE. UU.)

Más datos: nombres, identificadores, propiedades, ensayos y literatura

Nombres y definiciones oficiales

Nombre de etiquetado de la JCIA チオグリコール酸Na: 本品は、次の化学式で表される有機塩である。

Fuente: Nombres de etiquetado de la JCIA (Japón)

Nombres e identificadores

SODIUM THIOGLYCOLATEINCI소듐티오글라이콜레이트Nombre en etiquetas coreanas (estándar MFDS)Acetic acid, mercapto-, monosodium saltSinónimoチオグリコール酸NaNombre de etiquetado japonés
CAS No.número de registro químico
367-51-1
EC No.número de inventario químico de la UE
206-696-4
DTXSIDidentificador químico de la EPA (EE. UU.)
DTXSID3026142
DTXCIDidentificador de compuesto de la EPA (EE. UU.)
DTXCID806142
IUPAC
Sodium sulfanylacetate
Fórmula molecular
C2H3NaO2S
Peso molecular
114.09 g/mol

Propiedades medidas

Aspecto
Thioglycolic acid, sodium salt is a white powder with a slight odor. Used in cold-waving of hair and as a dipilatory. · Liquid
Punto de fusión
greater than 572 °F (NTP, 1992)
Solubilidad
Very soluble (NTP, 1992)
Punto de fusión/congelación
220 ℃
Peso molecular
114.10

Valores medidos en la sustancia en sí. Los datos de KOSHA son una referencia para redactar y revisar fichas de seguridad, no una especificación de una materia prima comercial.

Fuente: PubChem · Fichas de datos de seguridad de KOSHA (Corea)

Para qué lo usan los productos

Usos de los 13 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.

  • Degradant/impurity (EPA)4
  • Tanning agents not otherwise specified2
  • Reducing agent1
  • Hair waving or straightening (EPA)1
  • Depilatory (EPA)1
  • Cleaning agent1
  • Chelating agent1
  • Antioxidant1
1 usos más
  • Processing aids not otherwise specified1

Fuente: Panel CompTox de la EPA

Estudios de irritación y sensibilización

Constan 6 estudios en piel y 2 en ojos.

Clasificado como muy irritante2Clasificado como moderado1

Las conclusiones de los estudios coinciden en general (67%). Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.

Ver los 8 estudios
  • SkinSens1
    Skin Sensitization · QSAR Predicted
  • High Frequency of Sensitization
    skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay)
  • Skin irritation - category 2
    Skin Irritation · Screening
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Category 6.5B (Category 1)
    Skin Sensitization · Read Across
  • Moderate or Mild Irritation
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
  • Eye irritation - category 2A
    Eye Irritation · Screening
  • Moderate or Mild Irritation
    eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to

Fuente: Panel CompTox de la EPA

Literatura relacionada

Bases de datos vinculadas 19