Ingredient Dictionary

SODIUM TRICHLOROACETATE

TCA-sodium is an organic molecular entity.

Definition

TCA-sodium is an organic molecular entity.

Source: PubChem

US FDA substance register · UNII 2N76A3BRJ0 · registered name Sodium Trichloroacetate · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

SODIUM TRICHLOROACETATEINCI소듐트라이클로로아세테이트Korean label name (MFDS standard)

CAS No.chemical registry number: 650-51-1
EC No.EU chemical inventory number: 211-479-2
DTXSIDUS EPA chemical ID: DTXSID6034924
DTXCIDUS EPA compound ID: DTXCID4014924

IUPAC: Sodium trichloroacetate
Molecular formula: C2Cl3NaO2
Molecular weight: 185.36 g/mol

Measured properties

Appearance: Yellow deliquescent solid, [Merck Index] White to yellow hygroscopic solid, [ICSC] Off-white granules, [MSDSonline] · HYGROSCOPIC WHITE-TO-YELLOW POWDER.
Melting point: Decomposes at 165-200 °C
Solubility: In water = 1.2 kg/l at 25 °C · Soluble in ethanol
Density: Relative density (water = 1): 0.9
Dissociation constant: pKa = 0.64
Melting/freezing point: &amp, gt, 300 ℃
Initial boiling point and range: &amp, gt, 110 ℃
Flash point: 140 ℃
Vapour pressure: 0.0000000260 ㎜Hg (@ 25 °C)
Water solubility: 1200000 ㎎/ℓ
n-Octanol/water partition coefficient (Kow): 0.002
Molecular weight: 185.36

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Biocide2

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

7 skin studies and 4 eye studies are on record.

Classed as low5

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 11 studies

Not classified
Skin Irritation · Screening
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to
Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: Experimental design: analog HAZARDOUS SUBSTANCES, Part 191, Section 11, FDA, Washington 1965. according to
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation)
Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation)
Category 8.2C (Category 1C)
Skin Irritation · Read Across
Classification not possible
Skin Sensitization · Screening
Category 2B
Eye Irritation · Screening
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: Experimental design: analog HAZARDOUS SUBSTANCES, Part 191, Section 12, FDA, Washington 1965. according to
Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Category 8.3A (Category 1)
Eye Irritation · Read Across