Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups.
定义
美国FDA 物质登记 · UNII 2LRS185U6K · 登记名称 D&C RED NO. 27 · 单一化学物质
Phloxine O is a xanthene dye that is fluorescein in which the hydrogens at positions 2',4',5' and 7' are replaced by bromo groups, and the hydrogens at positions 4,5,6 and 7 are replaced by chloro groups. It is a red synthetic pigment which is widely used in colored cosmetics (e.g. lipsticks and blushers). It has a role as a fluorescent dye. It is a polyphenol, a tetrachlorobenzene, a dibromobenzene, a gamma-lactone, a xanthene dye, an oxaspiro compound, an organic heteropentacyclic compound and a member of 2-benzofurans. It is functionally related to a fluorescein (lactone form).
来源: PubChem
Solvent Red 48 is classed chemically as a fluoran color. It conforms to the formula. (To identify the colorant allowed for use in the European Union (EU), the INCI Name CI 45410 must be used, except for hair dye products).
化妆品中的作用
详细资料——标示名称、识别编号、物性、试验记录、文献
别名和识别信息
- CAS No.化学物质登记号
- 13473-26-2
- EC No.欧盟化学品目录编号
- 236-747-6
- DTXSID美国EPA化学品编号
- DTXSID2031089
- DTXCID美国EPA化合物编号
- DTXCID0011089
- IUPAC
- 2',4',5',7'-Tetrabromo-4,5,6,7-tetrachloro-3',6'-dihydroxy-3H-spiro[[2]benzofuran-1,9'-xanthen]-3-one
- 分子式
- C20H4Br4Cl4O5
- 分子量
- 785.66 g/mol
产品实际使用的用途
刺激与致敏试验记录
记录有皮肤试验 4 项、眼部试验 0 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 4 项试验
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD Guideline 402 (Acute Dermal Toxicity) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: As mentioned below - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: as below
来源: 美国EPA CompTox