3-[5-(Aminosulfonyl)benzoxazol-2-yl]-7-(diethylamino)coumarin is a member of coumarins.
Definition
US FDA substance register · UNII 05ZE90DQA4 · registered name 3-(5-(AMINOSULFONYL)BENZOXAZOL-2-YL)-7-(DIETHYLAMINO)COUMARIN · single chemical substance
3-[5-(Aminosulfonyl)benzoxazol-2-yl]-7-(diethylamino)coumarin is a member of coumarins.
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 68427-35-0
- EC No.EU chemical inventory number
- 270-393-3
- DTXSIDUS EPA chemical ID
- DTXSID6041476
- DTXCIDUS EPA compound ID
- DTXCID4021476
- IUPAC
- 2-[7-(Diethylamino)-2-oxo-2H-1-benzopyran-3-yl]-1,3-benzoxazole-5-sulfonamide
- Molecular formula
- C20H19N3O5S
- Molecular weight
- 413.45 g/mol
Measured properties
- Appearance
- Other Solid, Dry Powder
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Dye2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: OECD 402 according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: as mentioned below according to - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: As given below - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: As mentioned below according to - Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) 2010 according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) 2008 (including most recent amendments) according to EPA OPPTS 870.2600 (Skin Sensitisation) 2003 - Studies Indicate No Significant Irritation
eye irritation: in vitro / ex vivo · Screening · other guideline: OECD Guideline 437 (Bovine Corneal Opacity and Permeability Test Method for Identifying i) Chemicals Inducing Serious Eye Damage and ii) Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage) 2013 according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · other guideline: as mentioned below according to
Source: US EPA CompTox dashboard
Linked databases 11
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- PubChem 2
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata