Sphingosine 1-phosphate is a phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1.
Definition
US FDA substance register · UNII YVE187NJ1U · registered name SPHINGOSINE 1-PHOSPHATE · single chemical substance
Sphingosine 1-phosphate is a phosphosphingolipid that consists of sphingosine having a phospho group attached at position 1. It has a role as a vasodilator agent, a signalling molecule, a sphingosine-1-phosphate receptor agonist, a T-cell proliferation inhibitor and a mouse metabolite. It is functionally related to a sphingosine. It is a conjugate acid of a sphingosine 1-phosphate(1-).
Source: PubChem
Sphingosine 1-Phosphate is the phosphorylated sphingolipid that conforms to the formula:
Cosmetic roles
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name スフィンゴシン1-リン酸: 本品は、次の化学式で表されるリン酸化スフィンゴ脂質である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 26993-30-6
- DTXSIDUS EPA chemical ID
- DTXSID4037166
- DTXCIDUS EPA compound ID
- DTXCID2017166
- IUPAC
- (2S,3R,4E)-2-Amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
- Molecular formula
- C18H38NO5P
- Molecular weight
- 379.478 g/mol
Related literature
- Sphingosine 1-Phosphate Signaling at the Skin Barrier Interface · 2022
- Sphingosine 1-Phosphate Plays a Role in Maintaining the Integrity of Skin in Mice♦ · 2013
- Small EVs From Adipose‐Derived MSCs Modulate Epidermal Barrier and Inflammation Via Sphingosine‐1‐Phosphate Signaling Pathway · 2025
- The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis · 2023
- Sphingosine-1 phosphate prevents ethanol-induced corneal epithelial apoptosis · 2012
Linked databases 13
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese