Definition
US FDA substance register · UNII 4W9L3S4856 · registered name AFFININ · single chemical substance
Spilanthol is the organic compound that conforms to the formula
Cosmetic roles
Skin conditioning not covered aboveSKIN CONDITIONING - MISCELLANEOUSDraws moisture into the skinSKIN CONDITIONING - HUMECTANTProtects skin from outside irritantsSKIN PROTECTING
More data — names, identifiers, properties, test records, literature
Names & identifiers
SPILANTHOLINCI
- CAS No.chemical registry number
- 25394-57-4
- DTXSIDUS EPA chemical ID
- DTXSID90893963
- DTXCIDUS EPA compound ID
- DTXCID301324002
- IUPAC
- (2E,6Z,8E)-N-(2-Methylpropyl)deca-2,6,8-trienamide
- Molecular formula
- C14H23NO
- Molecular weight
- 221.344 g/mol
What products actually use it for
What the 1 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Flavouring and nutrient1
Source: US EPA CompTox dashboard
Related literature
- Modulation of Piceatannol Skin Diffusion by Spilanthol and UV Filters: Insights from the Strat-M™ Model · 2025
- Characteristic and use of spilanthol in cosmetology · 2021
- Investigation of Controlled Release Molecular Mechanism of Oil Phase in Spilanthol Emulsion: Development and In Vitro, In Vivo Characterization · 2019
- Topical Spilanthol Inhibits MAPK Signaling and Ameliorates Allergic Inflammation in DNCB-Induced Atopic Dermatitis in Mice · 2019
- A new approach for the total synthesis of spilanthol and analogue with improved anesthetic activity · 2018