1-phenylethanol is an aromatic alcohol that is ethanol substituted by a phenyl group at position 1.
Definition
1-phenylethanol is an aromatic alcohol that is ethanol substituted by a phenyl group at position 1. It has a role as a mouse metabolite.
Source: PubChem
US FDA substance register · UNII E6O895DQ52 · registered name 1-PHENYLETHANOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 98-85-1
- EC No.EU chemical inventory number
- 202-707-1
- DTXSIDUS EPA chemical ID
- DTXSID1020859
- DTXCIDUS EPA compound ID
- DTXCID50859
- IUPAC
- 1-Phenylethan-1-ol
- Molecular formula
- C8H10O
- Molecular weight
- 122.167 g/mol
Measured properties
- Appearance
- Alpha-methylbenzyl alcohol appears as a colorless liquid. Insoluble in water and less dense than water. Contact may slightly irritate skin, eyes and mucous membranes. May be slightly toxic by ingestion, inhalation and skin absorption. Used to make other chemicals. · Liquid
- Odour
- MILD FLORAL ODOR · MILD HYACINTH-GARDENIA ODOR
- Boiling point
- 399 °F at 745 mmHg (NTP, 1992) · 204 °C
- Melting point
- 68 °F (NTP, 1992) · 20.7 °C
- Solubility
- less than 1 mg/mL at 67.1 °F (NTP, 1992) · Sol in glycerol, mineral oil, alcohol
- Density
- 1.015 at 68 °F (USCG, 1999) - Denser than water, will sink · 1.013 @ 25 °C
- pH
- Neutral
- Colour
- colourless
- Melting/freezing point
- 20 ℃
- Initial boiling point and range
- 205 ℃
- Flash point
- 85 ℃(C.C.)
- Vapour pressure
- 0.058 ㎜Hg (25℃)
- Water solubility
- 1950 ㎎/ℓ (25℃)
- Vapour density
- 4.21
- Relative density
- 1.013 (25℃)
- n-Octanol/water partition coefficient (Kow)
- 1.490
- Molecular weight
- 122.17
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance3
- Flavouring and nutrient2
- Intermediate1
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
6 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 17%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Moderate or Mild Irritation
skin irritation: in vivo · Screening · other guideline: refer below principle according to - Not likely to be sensitizing
skin sensitisation · Screening · according to other guideline: Principle mentioned below - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to other guideline: Principle mentioned below - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · other guideline: refer below principle according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 17
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports
- Wikidata
- Wikipedia · English · Chinese