Styrene can cause cancer according to The National Toxicology Program.
Definition
Styrene can cause cancer according to The National Toxicology Program.
Source: PubChem
US FDA substance register · UNII 44LJ2U959V · registered name Styrene · single chemical substance
Styrene is the organic compound that conforms to the formula:
Cosmetic roles
Safety & regulatory references
- Banned
- ASEAN · European Union · United Kingdom
Source: ASEAN Cosmetic Directive · EU Cosmetics Regulation · MFDS (Korea) cosmetic regulatory information · UK cosmetics regulations (OPSS)
Korea’s toxic-substance GHS classification: Danger · H304 (category 1) · H372 (category 1) · H335 (category 3) · +6 more
EU Cosmetics Regulation, Annex II (prohibited substances), entry 1575
Restriction II/1575
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name スチレン: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 100-42-5
- EC No.EU chemical inventory number
- 202-851-5
- DTXSIDUS EPA chemical ID
- DTXSID2021284
- DTXCIDUS EPA compound ID
- DTXCID501284
- IUPAC
- Ethenylbenzene
- Molecular formula
- C8H8
- Molecular weight
- 104.152 g/mol
Measured properties
- Melting/freezing point
- -30.6 ℃
- Initial boiling point and range
- 145 ℃
- Flash point
- 31 ℃
- Upper/lower flammability or explosive limits
- 6.8 / 0.9 %
- Vapour pressure
- 0.67 ㎪(20℃)
- Water solubility
- 310 ㎎/ℓ(25℃)
- Vapour density
- 3.6
- Relative density
- 0.91
- n-Octanol/water partition coefficient (Kow)
- 2.95
- Auto-ignition temperature
- 490 ℃
- Decomposition temperature
- -4395.63 K
- Viscosity
- 0.696 cP(25℃)
- Molecular weight
- 104.14
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 226 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers151
- Binder39
- Fragrance4
- Intermediate4
- Filler3
- Processing aids not otherwise specified3
- Antioxidant2
- Viscosity modifier2
12 other uses
- Plating agent2
- Fuel2
- Pigment2
- Fuel agents2
- Surfactant (surface active agent)2
- Solvent2
- Elasticizer1
- Catalyst1
- Cleaning agent1
- Hardener1
- Diluent1
- Flavouring and nutrient1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 4 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Category 2
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Skin Irrit. 2
Skin Irritation · Screening - Skin Irrit. 2
Skin Irritation · Authoritative - Category 6.3A (Category 2)
Skin Irritation · Read Across - Eye Irrit. 2
Eye Irritation · Authoritative - Eye Irrit. 2
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 2A
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
- A Field Evaluation of Mandelic Acid in Urine as a Compliance Monitor for Styrene Exposure · 1990
- Styrene: Risk assessment, environmental, and health hazard · 2021
- An incident of massive styrene monomer gas poisoning · 2020
- Study on Styrene-acrylic Emulsion Used to Concrete Primer Sealer · 2009
- Contact allergy to styrene and related chemicals · 1984
Linked databases 26
- ASEAN Cosmetic Directive
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- EU Cosmetics Regulation
- EU prohibited substances (Annex II)
- IARC carcinogen classification
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UK cosmetics regulations (OPSS)
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- US National Toxicology Program reports 2 3
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese