Definition
US FDA substance register · UNII F9029V5818 · registered name TERT-BUTYL METHACRYLATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Methacrylate Ester Monomers
Reviewed by CIR: Final Report on the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name メタクリル酸ｔ－ブチル: 本品は、次の化学式で表される有機化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 585-07-9
- EC No.EU chemical inventory number
- 209-548-7
- DTXSIDUS EPA chemical ID
- DTXSID3060405
- DTXCIDUS EPA compound ID
- DTXCID8042399
- IUPAC
- tert-Butyl 2-methylprop-2-enoate
- Molecular formula
- C8H14O2
- Molecular weight
- 142.198 g/mol
Measured properties
- Appearance
- Tert-butyl methacrylate appears as a colorless liquid with an ester like odor. Less dense than water and insoluble in water. · Liquid
- Colour
- colourless
- Melting/freezing point
- -48 ℃
- Initial boiling point and range
- 132 ℃
- Flash point
- 27 ℃
- Vapour pressure
- 3 ㎜Hg (25℃)
- Relative density
- 0.88 (20℃)
- n-Octanol/water partition coefficient (Kow)
- 2.54 (log P=)
- Molecular weight
- 142.22
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 5 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Monomers3
- Film former1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
4 skin studies and 2 eye studies are on record.
The studies disagree (the most common conclusion covers 50%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 6 studies
- Severe Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Classification not possible
Skin Sensitization · Screening - Classification not possible
Skin Irritation · Screening - Classification not possible
Eye Irritation · Screening - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
- Synthesis and Characterization of Alkyl Methacrylate-based Microgels by Experimental Design Method · 2007
- Final Report of the Safety Assessment of Methacrylate Ester Monomers Used in Nail Enhancement Products1 · 2005
- Final report of the safety assessment of methacrylate ester monomers used in nail enhancement products. · 2005
Linked databases 17
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3 4
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese · Chinese