Tetraacetylethylenediamine is a dicarboximide.
Definition
US FDA substance register · UNII P411ED0N2B · registered name TETRAACETYLETHYLENEDIAMINE · single chemical substance
Tetraacetylethylenediamine is a dicarboximide.
Source: PubChem
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 10543-57-4
- EC No.EU chemical inventory number
- 234-123-8
- DTXSIDUS EPA chemical ID
- DTXSID5040752
- DTXCIDUS EPA compound ID
- DTXCID3020752
- IUPAC
- N,N'-(Ethane-1,2-diyl)bis(N-acetylacetamide)
- Molecular formula
- C10H16N2O4
- Molecular weight
- 228.248 g/mol
Measured properties
- Appearance
- Large Crystals, Dry Powder, Other Solid · Solid
- Melting point
- 149 - 150 °C
Values measured on the substance itself, not a specification for a commercial raw material.
Source: PubChem
What products actually use it for
What the 67 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chemical reaction regulator36
- Oxidizing agent17
- Bleaching agent12
- Cleaning agent1
- Surfactant (surface active agent)1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
5 skin studies and 3 eye studies are on record.
The studies disagree (the most common conclusion covers 25%), so they do not establish that this ingredient is irritating. These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 8 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EPA OPPTS 870.2600 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Moderate or Mild Irritation
skin irritation: in vivo · Screening · EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem 2
- Tlooto literature search
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Japanese