Testosterone is an androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4C-5..
Definition
Testosterone is an androstanoid having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4C-5.. It has a role as an androgen, a mouse metabolite, a human metabolite and a Daphnia magna metabolite. It is a C19-steroid, a 17beta-hydroxy steroid, a 3-oxo-Delta(4) steroid and an androstanoid.
Source: PubChem
US FDA substance register · UNII 3XMK78S47O · registered name TESTOSTERONE · single chemical substance
17β-Hydroxy-4-Androsten-3-one
Cosmetic roles
Safety & regulatory references
- Banned
- Argentina · ASEAN · Brazil · Canada · China · European Union · South Korea · Taiwan
Source: Health Canada Cosmetic Ingredient Hotlist · MFDS (Korea) cosmetic regulatory information
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Health Canada Cosmetic Ingredient Hotlist · prohibited in cosmetics
Restriction II/37
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 58-22-0
- EC No.EU chemical inventory number
- 200-370-5
- DTXSIDUS EPA chemical ID
- DTXSID8022371
- DTXCIDUS EPA compound ID
- DTXCID302371
- IUPAC
- 17beta-Hydroxyandrost-4-en-3-one
- Molecular formula
- C19H28O2
- Molecular weight
- 288.431 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Odour
- odourless
- Melting/freezing point
- 155 ℃
- Vapour pressure
- 0.000000017 ㎜Hg (at 25 ℃ (est))
- Water solubility
- 23.4 ㎎/ℓ (@ 25℃)
- Vapour density
- 9.96
- Relative density
- 1.17 (@ 20 ℃)
- n-Octanol/water partition coefficient (Kow)
- 3.32
- Molecular weight
- 288.43
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 10 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Pharmaceutical (EPA)9
- Softener and conditioner1
Source: US EPA CompTox dashboard
Related literature
- Testosterone Gel · 2020
- Variability in Serum Testosterone After Application of Testosterone Gel · 2015
- Is Oral Testosterone the New Frontier of Testosterone Replacement Therapy? · 2022
- Testosterone Vaginal Cream · 2020
- Testosterone 2% gel can normalize testosterone concentrations in men with low testosterone regardless of body mass index. · 2014
Linked databases 17
- ChEBI
- ChEMBL
- EU CosIng ingredient list 2
- Health Canada Cosmetic Ingredient Hotlist
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic regulatory information 2 3
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Korean · English · Japanese · Chinese