Definition
US FDA substance register · UNII VK5ZHH2T3F · registered name 2-ISOBUTYL-4-METHYLTETRAHYDROPYRAN-4-OL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 63500-71-0
- EC No.EU chemical inventory number
- 405-040-6
- DTXSIDUS EPA chemical ID
- DTXSID2052318
- DTXCIDUS EPA compound ID
- DTXCID3030890
- IUPAC
- 4-Methyl-2-(2-methylpropyl)oxan-4-ol
- Molecular formula
- C10H20O2
- Molecular weight
- 172.268 g/mol
Measured properties
- Appearance
- Dry Powder, Liquid, CBI · liquid
- Melting/freezing point
- &, lt, -100 ℃
- Initial boiling point and range
- 226.9 ℃
- Flash point
- 106 ℃
- Vapour pressure
- 0.01 hPa(20℃)
- Water solubility
- 23.653 g/ℓ(23°C)
- Relative density
- 0.95 (20℃)
- n-Octanol/water partition coefficient (Kow)
- 1.65 (23℃)
- Auto-ignition temperature
- 328 ℃
- Viscosity
- 234 mPa S((dynamic) (20 °C))
- Molecular weight
- 172.26
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 368 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Fragrance361
- Deodorizer4
- Flavouring and nutrient2
- Processing aids not otherwise specified1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 4 studies
- Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to EU Method B.6 (Skin Sensitisation) according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Severe Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Linked databases 13
- Australian Industrial Chemicals Inventory (AICIS)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata