Tetrakis(2-hydroxypropyl)ethylenediamine is an amino alcohol.
How much products actually contain
No product states its amount yet.
Of the products containing it, 6 list it before the 1% line and 19 after it (usually 1% or less).
Products using this ingredient
12 of 24 confirmed · likeliest to carry enough first · See all 24
Elizabeth ArdenElizabeth Arden PREVAGE® Anti-Aging Daily Serum 2.0
R+CoR+Co MANNEQUIN Styling Paste
DermalogicaDermalogica powerbright dark spot peel
TorridenBALANCEFUL Cica Pore Control Pack Cleanser
TorridenTorriden BALANCEFUL Cica Pore Control Pack Cleanser 120g
OGANACELLDerx Hydrate Cleanser
Mielle OrganicsMielle Organics Lavender & Lychee Scalp Soothing Daily Refresher
HaedalssiHAEDAL’S Deep Sea Balancing Cleansing Foam
SOME BY MIPDRN Spirulina Soothing Repair Serum
SOME BY MISOME BY MI PDRN Spirulina Soothing Repair Serum 50ml
OribeOribe Fiber Groom Elastic Texture Paste
make p:remmake p:rem Ion Splash Moisture Capsule Cream 80ml
Definition
Tetrakis(2-hydroxypropyl)ethylenediamine is an amino alcohol.
Source: PubChem
US FDA substance register · UNII Q4R969U9FR · registered name EDETOL · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name テトラヒドロキシプロピルエチレンジアミン: 本品は、次の化学式で表されるジアミンの誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 102-60-3
- EC No.EU chemical inventory number
- 203-041-4
- DTXSIDUS EPA chemical ID
- DTXSID9026689
- DTXCIDUS EPA compound ID
- DTXCID806689
- IUPAC
- 1,1',1'',1'''-(Ethane-1,2-diyldinitrilo)tetra(propan-2-ol)
- Molecular formula
- C14H32N2O4
- Molecular weight
- 292.42 g/mol
Measured properties
- Appearance
- liquid
- pH
- 9.5-10.5 ()
- Melting/freezing point
- &, lt, 25 ℃
- Initial boiling point and range
- 190 ℃(at 1㎜Hg)
- Flash point
- &, gt, 100 ℃
- Vapour pressure
- 0.00000000869 ㎜Hg (at 25℃)
- Water solubility
- 1 g/㎖
- Relative density
- 1.01-1.03
- n-Octanol/water partition coefficient (Kow)
- -2.08 ((est.))
- Auto-ignition temperature
- 200 ℃
- Viscosity
- 900 cP (at 60℃)
- Molecular weight
- 292.42
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 24 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chelating agent7
- Processing aids not otherwise specified3
- Plasticizer2
- Stabilizing agent2
- pH regulating agent2
- Catalyst2
- Sealant (barrier)1
- Monomers1
4 other uses
- Flame retardant1
- Cleaning agent1
- Fragrance1
- Plating agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 0 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- SkinIrr2
Skin Irritation · QSAR Predicted - SkinSens1
Skin Sensitization · QSAR Predicted
Source: US EPA CompTox dashboard
Related literature
- Cosmetic Lifting Effect of a Formula Combining Tetrahydroxypropyl Ethylenediamine, Ononis Spinosa and Glycerin as Shown by a New 2-D Imaging Method · 2013
- Allergic contact dermatitis caused by tetrahydroxypropyl ethylenediamine in cosmetic products · 2012
- Allergic contact dermatitis caused by tetrahydroxypropyl ethylenediamine in cosmetic products · 2011
- Clinical evidence for the activity of tetrahydroxypropyl ethylenediamine (THPE), a new anti-aging active cosmetic. · 2011
- Evaluation of the efficacy of a topical cosmetic slimming product combining tetrahydroxypropyl ethylenediamine, caffeine, carnitine, forskolin and retinol, In vitro, ex vivo and in vivo studies · 2011
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata