Definition
US FDA substance register · UNII 6IOT4Y7V2B · registered name 1,3,3,5-TETRAMETHYL-1,1,5,5-TETRAPHENYLTRISILOXANE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name テトラメチルテトラフェニルトリシロキサン: 本品は、次の化学式で表されるシロキサン化合物である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 103007-10-9
- CAS No.chemical registry number
- 3982-82-9
- EC No.EU chemical inventory number
- 223-620-5
- DTXSIDUS EPA chemical ID
- DTXSID2052073
- DTXCIDUS EPA compound ID
- DTXCID7030640
- IUPAC
- 1,3,3,5-Tetramethyl-1,1,5,5-tetraphenyltrisiloxane
- Molecular formula
- C28H32O2Si3
- Molecular weight
- 484.817 g/mol
Measured properties
- Appearance
- Liquid · Colorless to pale yellow liquid, [Aldrich MSDS]
- Vapour pressure
- 0.000000000586 ㎜Hg (25deg C)
- Water solubility
- 0.000000114 ㎎/ℓ (25deg C)
- n-Octanol/water partition coefficient (Kow)
- 10.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 4 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Lubricating agent2
- Softener and conditioner2
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) 1992 according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) 1987 according to
Source: US EPA CompTox dashboard
Linked databases 16
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata