Ingredient Dictionary

TETRAMETHYLAMMONIUM CHLORIDE

N,N,N-Trimethylmethanaminium chloride is an organic molecular entity.

Definition

N,N,N-Trimethylmethanaminium chloride is an organic molecular entity.

Source: PubChem

US FDA substance register · UNII DCQ9S88703 · registered name Tetramethylammonium chloride · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Adjusts thicknessVISCOSITY CONTROLLING

Safety & regulatory references

Korea’s toxic-substance GHS classification: Danger · H311 (category 3) · H300 (category 2) · H315 (category 2) · +1 more

Source: Korea toxic substances GHS register (NIER)

More data — names, identifiers, properties, test records, literature

Names & identifiers

TETRAMETHYLAMMONIUM CHLORIDEINCI테트라메틸암모늄클로라이드Korean label name (MFDS standard)Methanaminium, N,N,N-trimethyl-, chloride (1:1)Synonym

CAS No.chemical registry number: 75-57-0
EC No.EU chemical inventory number: 200-880-8
DTXSIDUS EPA chemical ID: DTXSID6021749
DTXCIDUS EPA compound ID: DTXCID301749

IUPAC: N,N,N-Trimethylmethanaminium chloride
Molecular formula: C4H12ClN
Molecular weight: 109.6 g/mol

Measured properties

Appearance: CBI, Liquid · White hygroscopic solid, [ICSC] White odorless powder, Hygroscopic, [Alfa Aesar MSDS]
Melting point: 420 °C (decomposes) · MP: Decomposes
Solubility: Slightly soluble in ethanol, insoluble in ether, benzene, chloroform, very soluble in methanol · Soluble in alcohol, insoluble in ether
Density: 1.1690 at 20 °C/4 °C · 1.17 g/cm³
Colour: white
Odour: odourless
Melting/freezing point: 268 ℃(at 101325 Pa)
Initial boiling point and range: 300 ℃
Upper/lower flammability or explosive limits: - / -
Vapour pressure: &amp, lt, 1.3 ㎩ (at 20℃)
Water solubility: 1000 g/ℓ(at 20ºC)
Relative density: 1.19
n-Octanol/water partition coefficient (Kow): -1.6 (at 20℃)
Molecular weight: 109.599

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 9 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Stabilizing agent2
Ion exchange agent1
Intermediate1
Chemical reaction regulator1
Processing aids not otherwise specified1
Hydraulic fluids1
Catalyst1
Viscosity modifier1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

2 skin studies and 1 eye studies are on record.

Classed as low1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 3 studies

Not likely to be sensitizing
skin sensitisation: in vivo (LLNA) · Screening · according to OECD Guideline 429 (Skin Sensitisation: Local Lymph Node Assay) according to EU Method B.42 (Skin Sensitisation: Local Lymph Node Assay) according to EPA OPPTS 870.2600 (Skin Sensitisation)
Skin irritation - category 2
Skin Irritation · Screening
Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) July 2010 according to EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) May 2008 according to EPA OPPTS 870.2400 (Acute Eye Irritation) March 2003 according to