Definition
US FDA substance register · UNII C23WAL597T · registered name DECAMETHYLTETRASILOXANE · single chemical substance
Tetrasiloxane is the linear siloxane that conforms to the formula:
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 141-62-8
- EC No.EU chemical inventory number
- 205-491-7
- DTXSIDUS EPA chemical ID
- DTXSID2044551
- DTXCIDUS EPA compound ID
- DTXCID0024551
- IUPAC
- Decamethyltetrasiloxane
- Molecular formula
- C10H30O3Si4
- Molecular weight
- 310.687 g/mol
Measured properties
- Appearance
- Liquid · Liquid, [Merck Index] Clear colorless liquid, [Acros Organics MSDS]
- Colour
- colourless
- Melting/freezing point
- -76 ℃(EXP)
- Initial boiling point and range
- 194 ℃(EXP)
- Flash point
- 62~63 ℃ (Closed cup)
- Vapour pressure
- 75 ㎩(25℃)
- Water solubility
- 0.007 ㎎/ℓ(23℃)
- Vapour density
- 10.7
- Relative density
- 0.8536 (25℃)
- n-Octanol/water partition coefficient (Kow)
- 5.4 (EXP)
- Auto-ignition temperature
- 350 ℃(1011.5 - 1022.2 hPa)
- Viscosity
- 1.35 cP(20℃)
- Molecular weight
- 310.69
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 8 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Diluent2
- Heat transferring agent1
- Lubricating agent1
- Intermediate1
- Fragrance1
- Solvent1
- Cleaning agent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EPA OPPTS 870.2500 (Acute Dermal Irritation) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · according to OECD Guideline 406 (Skin Sensitisation) according to EU Method B.6 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EPA OPPTS 870.2400 (Acute Eye Irritation) according to
Source: US EPA CompTox dashboard