How much products actually contain
No product states its amount yet.
Of the products containing it, 0 list it before the 1% line and 350 after it (usually 1% or less).
Products using this ingredient
12 of 350 confirmed · likeliest to carry enough first · See all 350
SaeangmeoriEoyumi Liquid Shampoo
Calvin KleinCK One/Be/Moisturizer/Essence Perfume Intense/Mist
Calvin KleinCK One EDT (Single/Set)
Dr.deepAtoDeep Soap
Harry'sHarry's Sculpting Gel 6.7oz
Paul MitchellPaul Mitchell Tea Tree Special Conditioner Aluminum Bottle
PATTERN BeautyPATTERN Beauty Indigo Rain Strong Hold Gel
PATTERN BeautyPATTERN Beauty Strong Hold Gel
DonggubatDonggubat Facial Cleansing Soap Collagen
Nano Doctor PlusBaby Soap
MenthologySUPER COOL SHAMPOO
American CrewAmerican Crew FIRM HOLD STYLING GEL
Definition
US FDA substance register · UNII MP1J8420LU · registered name EDETATE SODIUM · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: EDTA and Salts
Reviewed by CIR: Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, HEDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, and Trisodium HEDTA
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name ＥＤＴＡ－４Ｎａ: 本品は、エチレンジアミン四酢酸（ＥＤＴＡ（＊））の四ナトリウム塩であり、次の化学式で表されるジアミン誘導体である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 64-02-8
- EC No.EU chemical inventory number
- 200-573-9
- DTXSIDUS EPA chemical ID
- DTXSID3026350
- DTXCIDUS EPA compound ID
- DTXCID706350
- IUPAC
- Tetrasodium 2,2',2'',2'''-(ethane-1,2-diyldinitrilo)tetraacetate
- Molecular formula
- C10H12N2Na4O8
- Molecular weight
- 380.171 g/mol
Measured properties
- Appearance
- Liquid, Other Solid, CBI, Dry Powder, Wet Solid, Large Crystals · White solid, [Hawley] Colorless solid, [ICSC] White, slightly yellow, or cream-colored solid, Hygroscopic, [CHEMINFO]
- Melting point
- 300 °C (decomposes)
- Solubility
- Slightly soluble in ethanol · Less soluble in alcohol than the potassium salt
- Density
- 6.9 lb/gal /Apparent density/ · Relative density (water = 1): 0.7
- pH
- pH of 1% soln: 11.3 · 11.3
- Colour
- colourless
- Flammability (solid, gas)
- not flammable
- Upper/lower flammability or explosive limits
- - / -
- Vapour pressure
- 0.00000000000149 ㎜Hg (25 ℃, est.)
- Water solubility
- 1000000 ㎎/ℓ (25 ℃)
- Vapour density
- 13.12
- Relative density
- 0.7
- n-Octanol/water partition coefficient (Kow)
- -13.17 (est.)
- Auto-ignition temperature
- (&, gt, 200℃)
- Decomposition temperature
- 300 ℃
- Molecular weight
- 380.171
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 578 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chelating agent537
- Preservative8
- Processing aids not otherwise specified6
- Anti-scaling agent6
- Corrosion inhibitor5
- Ion exchange agent3
- Anti-adhesive/cohesive2
- Surfactant (surface active agent)2
8 other uses
- Cleaning agent2
- Surface modifier1
- Soil amendments1
- Adhesion/cohesion promoter1
- Fragrance1
- Stabilizing agent1
- Thickening agent1
- Intermediate1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 6 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 9 studies
- Not classified
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to - Serious eye damage/eye irritation - Category 2
Eye Irritation · Screening - Category 2A
Eye Irritation · Screening - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Eye Dam. 1
Eye Irritation · Authoritative - Severe Irritation
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to - Corrosive or Irritation Persists for > 21 days
eye irritation: in vivo · Screening · OECD Guideline 405 (Acute Eye Irritation / Corrosion) equivalent or similar to
Source: US EPA CompTox dashboard
Related literature
- A Study on the Antimicrobial Synergies of Alternative Preservatives and Chelating Agents · 2024
- EDTA: An Antimicrobial and Antibiofilm Agent for Use in Wound Care · 2015
- Contact allergy to tetrasodium EDTA in a sunscreen · 2009
- Final Report on the Safety Assessment of EDTA, Calcium Disodium EDTA, Diammonium EDTA, Dipotassium EDTA, Disodium EDTA, TEA-EDTA, Tetrasodium EDTA, Tripotassium EDTA, Trisodium EDTA, HEDTA, and Trisodium HEDTA · 2002
Linked databases 19
- Australian Industrial Chemicals Inventory (AICIS)
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search 2 3 4
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2 3
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · English · Chinese