How much products actually contain
No product states its amount yet.
Of the products containing it, 142 list it before the 1% line and 363 after it (usually 1% or less).
Products using this ingredient
12 of 505 confirmed · likeliest to carry enough first · See all 505
OLAPLEXOLAPLEX Pro Exclusive: Broad Spectrum Chelating Treatment
Mielle OrganicsMielle Organics Avocado & Tamanu Anti-Frizz Shampoo
The Body ShopThe Body Shop Olive Cleansing Face & Body Bar
The Body ShopThe Body Shop Pink Grapefruit Cleansing Face & Body Bar
Not Your Mother'sNot Your Mother's Fragrance & Protein Free Defining Cream
The Body ShopThe Body Shop Satsuma Cleansing Face & Body Bar
Paul MitchellPaul Mitchell Hold Me Tight Hairspray
Not Your Mother'sNot Your Mother's Defining Spray Gel
Not Your Mother'sNot Your Mother's Root Lift Spray
Not Your Mother'sNot Your Mother's Ultimate Nutrition Shampoo
The Body ShopThe Body Shop Almond Milk Cleansing Face & Body Bar
Tower 28Tower 28 SOS Rescue + Relief Body Wash Treatment
Definition
US FDA substance register · UNII 5EHL50I4MY · registered name TETRASODIUM GLUTAMATE DIACETATE · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Safety Assessment of Tetrasodium Glutamate Diacetate and Beta-Alanine Diacetic Acid as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name グルタミン酸ジ酢酸４Ｎａ: 本品は、グルタミン酸（＊）の誘導体であり、次の化学式で表される。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 51981-21-6
- EC No.EU chemical inventory number
- 257-573-7
- DTXSIDUS EPA chemical ID
- DTXSID2052158
- DTXCIDUS EPA compound ID
- DTXCID7030727
- IUPAC
- Tetrasodium N,N-bis(carboxylatomethyl)-L-glutamate
- Molecular formula
- C9H9NNa4O8
- Molecular weight
- 351.129 g/mol
Measured properties
- Appearance
- Liquid, Other Solid, Dry Powder, CBI
- Initial boiling point and range
- 125 ℃
- Vapour pressure
- 81 ㎩ (21 degrees C)
- Relative density
- 1.466
- n-Octanol/water partition coefficient (Kow)
- &, lt, 3.7 (20°C)
- Decomposition temperature
- 280 ℃
- Molecular weight
- 351.13
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 65 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Chelating agent60
- Ion exchange agent2
- Processing aids not otherwise specified1
- Cleaning agent1
- Solvent1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
2 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 3 studies
- Studies Indicate No Significant Irritation
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to EU Method B.4 (Acute Toxicity: Dermal Irritation / Corrosion) according to - Not likely to be sensitizing
skin sensitisation: in vivo (non-LLNA) · Screening · equivalent or similar to OECD Guideline 406 (Skin Sensitisation) according to other guideline: MAFF 59 NohSan No. 4200 according to EPA OPP 81-6 (Skin Sensitisation) according to EPA OTS 798.4100 (Skin Sensitisation) - Studies Indicate No Significant Irritation
eye irritation: in vivo · Screening · EU Method B.5 (Acute Toxicity: Eye Irritation / Corrosion) according to OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to
Source: US EPA CompTox dashboard
Related literature
Linked databases 18
- AICIS inventory notices (Australia)
- Australian Industrial Chemicals Inventory (AICIS)
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem
- Tlooto literature search
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata