Ingredient Dictionary

THIABENDAZOLE

Thiabendazole is a member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2.

Definition

Thiabendazole is a member of the class of benzimidazoles carrying a 1,3-thiazol-4-yl substituent at position 2. A mainly post-harvest fungicide used to control a wide range of diseases including Aspergillus, Botrytis, Cladosporium and Fusarium. It has a role as an antinematodal drug and an antifungal agrochemical. It is a member of benzimidazoles, a member of 1,3-thiazoles and a benzimidazole fungicide. It derives from a hydride of a 1H-benzimidazole.

Source: PubChem

US FDA substance register · UNII N1Q45E87DT · registered name Thiabendazole · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Inhibits microbial growthANTIMICROBIAL

Safety & regulatory references

Banned: ASEAN

Source: ASEAN Cosmetic Directive

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

THIABENDAZOLEINCI티아벤다졸Korean label name (MFDS standard)1H-Benzimidazole, 2-(4-thiazolyl)-Synonym

CAS No.chemical registry number: 148-79-8
EC No.EU chemical inventory number: 205-725-8
DTXSIDUS EPA chemical ID: DTXSID0021337
DTXCIDUS EPA compound ID: DTXCID401337

IUPAC: 2-(1,3-Thiazol-4-yl)-1H-1,3-benzimidazole
Molecular formula: C10H7N3S
Molecular weight: 201.25 g/mol

Measured properties

Appearance: Thiabendazole appears as white or cream-colored odorless, tasteless powder. Sublimes above 590 °F. Fluoresces in acidic solution. Formulated as a dust, flowable powder or wettable powder for use as a systemic fungicide and anthelmintic. · Colorless, white, or tan odorless solid, [HSDB] Colorless solid, [EPA REDs] Off-white to yellow-tan solid, [CPSQ]
Odour: Odorless · odourless
Melting point: 579 to 581 °F (NTP, 1992) · 300 °C
Solubility: less than 1 mg/mL at 70 °F (NTP, 1992) · 50 mg/L (at 25 °C)
Density: Amber liquid, density: 1.103 at 25 °C /Thiabendazole hypophosphite/
Stability: Non-volatile at room temp, stable in water and in acid and alkaline soln, stable under normal conditions to hydrolysis, light, and heat.
Dissociation constant: 4.64 (at 25 °C) · pKa = 4.64
Melting/freezing point: 304~305 ℃
Water solubility: 50 ㎎/ℓ (25℃)
n-Octanol/water partition coefficient (Kow): 2.47
Molecular weight: 201.25

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 179 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Biocide173
Degradant/impurity (EPA)4
Processing aids not otherwise specified2

Source: US EPA CompTox dashboard