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Ingredient Dictionary

THIOCTIC ACID

Lipoic acid is a heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position.

Molecular structure

How much products actually contain

No product states its amount yet.

Of the products containing it, 8 list it before the 1% line and 43 after it (usually 1% or less).

Products using this ingredient

12 of 51 confirmed · likeliest to carry enough first · See all 51

Definition

Lipoic acid is a heterocyclic thia fatty acid comprising pentanoic acid with a 1,2-dithiolan-3-yl group at the 5-position. It has a role as a geroprotector and a fundamental metabolite. It is a member of dithiolanes, a heterocyclic fatty acid and a thia fatty acid. It is functionally related to an octanoic acid. It is a conjugate acid of a lipoate.

Source: PubChem

US FDA substance register · UNII 73Y7P0K73Y · registered name ALPHA LIPOIC ACID · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANT

Safety & regulatory references

Japan

  • Maximum amount per 100 g (Cosmetics not used for mucosa and to be washed away) : 0.01 g
  • Maximum amount per 100 g (Cosmetics not used for mucosa and not to be washed away) : 0.01 g

Source: MFDS (Korea) cosmetic regulatory information

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Official labels & definitions

JCIA labelling name チオクト酸: 本品は、次の化学式で表される含硫複素環式化合物である。

Source: JCIA labelling names (Japan)

Names & identifiers

THIOCTIC ACIDINCI티옥틱애씨드Korean label name (MFDS standard)1,2-Dithiolane-3-pentanoic acidSynonymチオクト酸Japanese labelling name
CAS No.chemical registry number
1077-28-7
EC No.EU chemical inventory number
214-071-2
DTXSIDUS EPA chemical ID
DTXSID7025508
DTXCIDUS EPA compound ID
DTXCID705508
IUPAC
5-(1,2-Dithiolan-3-yl)pentanoic acid
Molecular formula
C8H14O2S2
Molecular weight
206.32 g/mol

Measured properties

Appearance
yellow needles from cyclohexane
Melting/freezing point
60~61 ℃
Initial boiling point and range
160~165 ℃
Water solubility
126.6 ㎎/ℓ
n-Octanol/water partition coefficient (Kow)
3.40
Molecular weight
206.34

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: KOSHA safety data sheets (Korea)

What products actually use it for

What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

  • Antioxidant2

Source: US EPA CompTox dashboard

Related literature

Linked databases 20