Thiodiacetic acid is a dicarboxylic acid.
Definition
Thiodiacetic acid is a dicarboxylic acid.
Source: PubChem
US FDA substance register · UNII 483M3RG5GW · registered name THIODIGLYCOLIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
More data — names, identifiers, properties, test records, literature
Names & identifiers
- CAS No.chemical registry number
- 123-93-3
- EC No.EU chemical inventory number
- 204-663-9
- DTXSIDUS EPA chemical ID
- DTXSID1051432
- DTXCIDUS EPA compound ID
- DTXCID0030033
- IUPAC
- 2,2'-Sulfanediyldiacetic acid
- Molecular formula
- C4H6O4S
- Molecular weight
- 150.15 g/mol
Measured properties
- Appearance
- Colorless or white solid, [HSDB] Tan powder, [Alfa Aesar MSDS] · Solid
- Melting point
- 129 °C
- Solubility
- Very soluble in ethanol, soluble in benzene · In water, 4X10+5 mg/l @ 25 deg
- Colour
- white
- Melting/freezing point
- 129 ℃
- Flammability (solid, gas)
- combustible
- Water solubility
- 400000 ㎎/ℓ (@ 25 ℃)
- Vapour density
- 5.18
- n-Octanol/water partition coefficient (Kow)
- -1.16 (est.)
- Molecular weight
- 150.16
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: PubChem · KOSHA safety data sheets (Korea)
What products actually use it for
What the 2 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Reducing agent1
- Antioxidant1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
1 skin studies and 1 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 2 studies
- Category 6.3A (Category 2)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across
Source: US EPA CompTox dashboard
Related literature
- Author index · 2005
- Carbocisteine‐induced Stevens–Johnson syndrome confirmed by inadvertent re‐exposure · 2022
- [14C]bis(2-chloroethoxy)methane: Comparative absorption, distribution, metabolism and excretion in rats and mice · 2007
- Thiodiglycolic acid and dermatological reactions following S‐carboxymethyl‐l‐cysteine administration · 2006
- Thiodiglycolic acid as a possible causative agent of fixed drug eruption provoked only after continuous administration of S‐carboxymethyl‐l‐cysteine: case report and review of reported cases · 2005
Linked databases 18
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- PubChem 2
- Tlooto literature search 2 3 4 5
- UniChem cross-reference IDs
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata
- Wikipedia · Chinese