3,3'-Thiobispropanoic acid is a dicarboxylic acid.
Definition
3,3'-Thiobispropanoic acid is a dicarboxylic acid.
Source: PubChem
US FDA substance register · UNII 3BBK323ED8 · registered name THIODIPROPIONIC ACID · single chemical substance
Cosmetic roles
Safety & regulatory references
Not classified under Korea’s toxic-substance GHS list · existing chemical substance
Other restriction: ban substances that deplete the ozone layer
Source: EU CosIng ingredient list
Reviewed by CIR: Final Safety Assessment of Thiodipropionic Acid and its Dialkyl Esters as Used in Cosmetics
More data — names, identifiers, properties, test records, literature
Official labels & definitions
JCIA labelling name チオジプロピオン酸: 本品は、次の化学式で表される含硫カルボン酸である。
Source: JCIA labelling names (Japan)
Names & identifiers
- CAS No.chemical registry number
- 111-17-1
- EC No.EU chemical inventory number
- 203-841-3
- DTXSIDUS EPA chemical ID
- DTXSID8044200
- DTXCIDUS EPA compound ID
- DTXCID6024200
- IUPAC
- 3,3'-Sulfanediyldipropanoic acid
- Molecular formula
- C6H10O4S
- Molecular weight
- 178.2 g/mol
Measured properties
- Appearance
- solid
- Colour
- white
- Melting/freezing point
- 123~134 ℃
- Flash point
- 126~129 ℃
- Water solubility
- 37200 ㎎/ℓ
- n-Octanol/water partition coefficient (Kow)
- -0.18
- Molecular weight
- 178.21
Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.
Source: KOSHA safety data sheets (Korea)
What products actually use it for
What the 7 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.
- Processing aids not otherwise specified2
- Antioxidant2
- Softener and conditioner1
- Monomers1
- Catalyst1
Source: US EPA CompTox dashboard
Irritation and sensitisation studies
3 skin studies and 2 eye studies are on record.
The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.
See all 5 studies
- Category 1
Skin Irritation · Screening - Classification not possible
Skin Sensitization · Screening - Category 6.3B (Category 3)
Skin Irritation · Read Across - Category 6.4A (Category 2A)
Eye Irritation · Read Across - Category 1
Eye Irritation · Screening
Source: US EPA CompTox dashboard
Related literature
Linked databases 20
- Australian Industrial Chemicals Inventory (AICIS)
- ChEBI
- ChEMBL
- China inventory of existing ingredients (IECIC)
- EU CosIng ingredient list 2
- JCIA labelling names (Japan)
- Korea Cosmetic Association ingredient dictionary
- Korea toxic substances GHS register (NIER)
- KOSHA safety data sheets (Korea)
- MFDS (Korea) cosmetic ingredient register 2
- NIST Chemistry WebBook
- PubChem
- Tlooto literature search 2
- UniChem cross-reference IDs
- US Cosmetic Ingredient Review (CIR) 2
- US EPA CompTox dashboard 2
- US EPA DSSTox chemical database
- US FDA substance registration (GSRS)
- US FDA Unique Ingredient Identifier (UNII)
- Wikidata