Thioglycolic acid is a sulfur-containing carboxylic acid.
产品中实际含有多少
暂无产品标示该成分含量。
含该成分的产品中,1 款将其列在 1% 线之前,1 款列在之后(通常不超过 1%)。
含有此成分的产品
已确认 2 款中的 2 款 · 按含量充足程度排序
定义
Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-).
来源: PubChem
美国FDA 物质登记 · UNII 7857H94KHM · 登记名称 Thioglycolic acid · 单一化学物质
Thioglycolic Acid is the organic acid that conforms generally to the formula:
化妆品中的作用
安全与法规参考
- 限用
- 韩国 · 英国
来源: 东盟化妆品指令 · 欧盟化妆品法规 · 加拿大禁用·限用成分清单 · 韩国食药处 化妆品法规信息 · 台湾FDA 化妆品成分 · 台湾FDA 化妆品法规 · 英国化妆品法规
阿根廷 · 巴西
- Field of application and/or use : (a) Products for hair straightening or waving: 1. General use 2. Professional use (b) Depilatories (c) Other products for hair care which are removed after application
- Maximum concentration permitted at final product : (a) 1. 8% ready to use pH 7 to 9.5 2. 11% ready to use pH 7 to 9.5 (b) 5% ready to use pH 7 to 12.7 (c) 2% .ready to use pH 7 to 9.5 The indicated percentages are calculated as thioglycolic acid
- Other limitations and requirements : a, b and c) In the USAGE must obligatorily the following information recorded: - Avoid contact with eyes. - In case of contact with eyes, rinse immediately with plenty water and consult a doctor - and c) Wear suitable gloves
- Use conditions and warnings that must appear on the label : a), b) and c) - Contains thioglycolic acid salts - Follow instructions - Keep out of reach of children - Only for professional use (where appropriate)
东盟
- Field of application and/or use : (a) Hair waving or straightening products: 1. General use 2. Professional use (b) Depilatories (c) Other hair care products which are removed after application
- Maximum authorised concentration in the finished cosmetic product : (a) 1. 8% ready for use at pH 7 – 9.5 2. 11% ready for use at pH 7- 9.5 (b) 5% ready for use at pH 7-12.7 (c) 2% ready for use at pH 7-9.5 For general use of hair waving or straightening products the maximum concentration for combination of Thioglycolic acid and thiolactic acid must not exceed 8% calculated as Thioglycolic Acid.
- Other limitations and requirements : (a) (b) (c) The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • Avoid contact with eyes • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves (a) and (c) only.
- Conditions of use and warning which must be printed on the labels : (a) • Contains thioglycolate • Follow the instructions • Keep out of reach of children. • For professional use only. (b) and (c) • Contains thioglycolate • Follow the instructions • Keep out of reach of children
加拿大
- Conditions of Use by product type : (a) Eyelash curling products (b) Hair dyes, waving or straightening products (c) Hair dyes, waving or straightening products for professional use (d) Depilatory products
- Maximum Concentration Permitted : ((a) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (b) 8% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (c) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (d) 5% (as thioglycolic aci(d) with a pH less than or equal to 12.7
- Warnings and Cautionary Statements: (to the effect of) : (a) "For professional use only.", "Avoid direct skin contact, wear suitable gloves.", "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention." (b)"Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." (c) "For professional use only." "Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." d) "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention."
台湾
- ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
- ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
- ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
- ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
- 用途 : 使用限制
- 最大配合量 : (a)燙髮產品 : (a1)8% (以thioglycollic acid 計)
- (a2)11% (以 thioglycollic acid 計)
- (b)立即沖洗之髮用產品 : 2%( 以 thioglycollic acid 計)
- (a2)11%
- (b)含 thioglycolate; 使用前請詳閱說明書,並依據使用方法正確使用;應放置於孩童伸手不及之場所儲存。
中国
- 最大配合量 : (a)
欧盟
- Product Type, body parts : (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
- Maximum concentration in ready for use preparation : (a) 1) 8% 2) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
- Other : (a) General use ready for use pH 7 to 9.5 Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5
- Wording of conditions of use and warnings : Condition of use: (a) (b) (c) Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a) (d) For professional use only: Cotains thiglycolata, folow the instruction.
来源: 韩国食药处 化妆品法规信息
韩国有毒物质 GHS 分类: 危险 · H311 (第3类) · H330 (第2类) · H301 (第3类) · 另有 1 项
欧盟化妆品法规 附录III(限用物质) 第2a项 · 最高浓度 (a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid · 适用 (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
来源: 欧盟限用成分(附录III)
Restriction III/2a · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Thioglycolic acid and its salts (TGA)
来源: 欧盟 CosIng 成分清单
Reviewed by CIR: Final Report on the Safety Assessment of Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid
来源: 美国CIR 安全性评估
Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid
来源: 美国CIR 安全性评估
详细资料——标示名称、识别编号、物性、试验记录、文献
官方标示名称和定义
日本化妆品工业联合会标示名称 チオグリコール酸: 本品は、次の化学式で表される有機酸である。
来源: 日本化妆品工业联合会标示名称
别名和识别信息
- CAS No.化学物质登记号
- 68-11-1
- EC No.欧盟化学品目录编号
- 200-677-4
- DTXSID美国EPA化学品编号
- DTXSID8026141
- DTXCID美国EPA化合物编号
- DTXCID406141
- IUPAC
- Sulfanylacetic acid
- 分子式
- C2H4O2S
- 分子量
- 92.11 g/mol
实测物性
- 颜色
- 无色
- pH
- 1.6
- 熔点/凝固点
- -16.5 ℃
- 初沸点和沸程
- 120 ℃
- 闪点
- 126 ℃(o.c.)
- 燃烧或爆炸范围上限/下限
- 5.9 / - % (in air)
- 蒸气压
- 0.0868 ㎜Hg(25℃)
- 溶解度
- 100 g/100㎖(25℃)
- 蒸气密度
- 3.18
- 比重
- 1.3 (20℃)
- 正辛醇/水分配系数(Kow)
- -2.99
- 自燃温度
- 350 ℃
- 黏度
- 6.55 mPa S(20℃, mPa s)
- 分子量
- 92.1
这是对物质本身测得的数值。韩国安全保健公团(KOSHA)的资料仅供编写和审核安全数据表参考,并非原料商品的规格。
来源: 韩国安全保健公团 安全数据表
产品实际使用的用途
这是向美国 EPA 申报含该成分的 23 款产品的用途。其中包括化妆品以外的产品,排在前几行的即为该成分的主要用途。
- Depilatory (EPA)9
- Reducing agent5
- Hair waving or straightening (EPA)1
- Catalyst1
- Surfactant (surface active agent)1
- Processing aids not otherwise specified1
- Flotation agent1
- Corrosion inhibitor1
其余用途 3 项
- Antioxidant1
- Heat stabilizer1
- Intermediate1
来源: 美国EPA CompTox
刺激与致敏试验记录
记录有皮肤试验 10 项、眼部试验 2 项。
试验结论基本一致(100%)。 这是对原料本身的试验记录,与成品中所含浓度下的刺激性不同。
查看全部 12 项试验
- Skin sensitization - Category 1
Skin Sensitization · Screening - Skin corrosion - category 1
Skin Irritation · Screening - Sh
Skin Sensitization · Authoritative - Skin sensitisation - category 1
Skin Sensitization · Screening - Category 1
Skin Sensitization · Screening - Category 1
Skin Irritation · Screening - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Skin Corr. 1B
Skin Irritation · Authoritative - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
来源: 美国EPA CompTox
相关文献
- Effect of Thioglycolic Acid Instillation to Stop Hair Growth on the Urethral Mucosa after Urethroplasty with Hairy Skin in a Rat Model · 2010
- Thioglycolic acid peeling as a therapy for post-inflammatory hyperchromia · 2015
- A Study on a Method of Detecting Heavy Metal Content Using Thioglycolic Acid and Quartz Crucible · 2024
- Colorimetric detection of thioglycolic acid based on the enhanced Fe3+ ions Fenton reaction · 2019
- A Survey on Health Effects in a Human Population Exposed to Permanent‐Waving Solution Containing Thioglycolic Acid · 2003
关联数据库 30
- 澳大利亚工业化学品名录(AICIS)
- 东盟化妆品指令
- 韩国安全保健公团 安全数据表
- 韩国化妆品协会成分词典
- 韩国食药处 化妆品法规信息 2 3 4
- 韩国食药处 化妆品原料成分 2
- 韩国有毒物质 GHS 信息(环境公团)
- 加拿大禁用·限用成分清单
- 美国CIR 安全性评估 2 3
- 美国EPA 化学品数据库(DSSTox)
- 美国EPA CompTox 2
- 美国FDA 物质登记(GSRS)
- 美国FDA 物质识别码(UNII)
- 欧盟 CosIng 成分清单 2
- 欧盟 SCCS 安全意见
- 欧盟化妆品法规
- 欧盟限用成分(附录III)
- 日本化妆品工业联合会标示名称
- 台湾FDA 化妆品成分
- 台湾FDA 化妆品法规
- 英国化妆品法规
- 中国已使用化妆品原料目录(IECIC)
- ChEBI
- ChEMBL
- NIST 化学网络手册
- PubChem
- Tlooto 学术文献检索 2 3 4 5
- UniChem 化学物质统一 ID
- Wikidata
- Wikipedia · 英语 · 日语 · 中文