Thioglycolic acid is a sulfur-containing carboxylic acid.
Cuánto contienen realmente los productos
Ningún producto indica todavía su cantidad.
De los productos que lo contienen, 1 lo listan antes de la línea del 1% y 1 después (normalmente 1% o menos).
Productos que contienen este ingrediente
2 de 2 confirmados · primero los que más probablemente lo contienen en cantidad suficiente
Definición
Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-).
Fuente: PubChem
Registro de sustancias de la FDA (EE. UU.) · UNII 7857H94KHM · nombre registrado Thioglycolic acid · sustancia química única
Fuente: Identificador único de ingredientes de la FDA (UNII)
Thioglycolic Acid is the organic acid that conforms generally to the formula:
Funciones cosméticas
Referencias de seguridad y regulación
- Restringido
- Corea del Sur · Reino Unido
Fuente: Directiva cosmética de la ASEAN · Reglamento de cosméticos de la UE · Lista de ingredientes restringidos de Health Canada · Información regulatoria cosmética del MFDS (Corea) · Ingredientes cosméticos de la FDA de Taiwán · Normativa cosmética de la FDA de Taiwán · Normativa cosmética del Reino Unido (OPSS)
Argentina · Brasil
- Field of application and/or use : (a) Products for hair straightening or waving: 1. General use 2. Professional use (b) Depilatories (c) Other products for hair care which are removed after application
- Maximum concentration permitted at final product : (a) 1. 8% ready to use pH 7 to 9.5 2. 11% ready to use pH 7 to 9.5 (b) 5% ready to use pH 7 to 12.7 (c) 2% .ready to use pH 7 to 9.5 The indicated percentages are calculated as thioglycolic acid
- Other limitations and requirements : a, b and c) In the USAGE must obligatorily the following information recorded: - Avoid contact with eyes. - In case of contact with eyes, rinse immediately with plenty water and consult a doctor - and c) Wear suitable gloves
- Use conditions and warnings that must appear on the label : a), b) and c) - Contains thioglycolic acid salts - Follow instructions - Keep out of reach of children - Only for professional use (where appropriate)
ASEAN
- Field of application and/or use : (a) Hair waving or straightening products: 1. General use 2. Professional use (b) Depilatories (c) Other hair care products which are removed after application
- Maximum authorised concentration in the finished cosmetic product : (a) 1. 8% ready for use at pH 7 – 9.5 2. 11% ready for use at pH 7- 9.5 (b) 5% ready for use at pH 7-12.7 (c) 2% ready for use at pH 7-9.5 For general use of hair waving or straightening products the maximum concentration for combination of Thioglycolic acid and thiolactic acid must not exceed 8% calculated as Thioglycolic Acid.
- Other limitations and requirements : (a) (b) (c) The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • Avoid contact with eyes • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves (a) and (c) only.
- Conditions of use and warning which must be printed on the labels : (a) • Contains thioglycolate • Follow the instructions • Keep out of reach of children. • For professional use only. (b) and (c) • Contains thioglycolate • Follow the instructions • Keep out of reach of children
Canadá
- Conditions of Use by product type : (a) Eyelash curling products (b) Hair dyes, waving or straightening products (c) Hair dyes, waving or straightening products for professional use (d) Depilatory products
- Maximum Concentration Permitted : ((a) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (b) 8% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (c) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (d) 5% (as thioglycolic aci(d) with a pH less than or equal to 12.7
- Warnings and Cautionary Statements: (to the effect of) : (a) "For professional use only.", "Avoid direct skin contact, wear suitable gloves.", "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention." (b)"Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." (c) "For professional use only." "Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." d) "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention."
Taiwán
- (a2)11%
China
- Concentración máxima : (a)
Unión Europea
- Product Type, body parts : (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
- Maximum concentration in ready for use preparation : (a) 1) 8% 2) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
- Other : (a) General use ready for use pH 7 to 9.5 Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5
- Wording of conditions of use and warnings : Condition of use: (a) (b) (c) Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a) (d) For professional use only: Cotains thiglycolata, folow the instruction.
Fuente: Información regulatoria cosmética del MFDS (Corea)
Clasificación GHS de sustancias tóxicas de Corea: Peligro · H311 (categoría 3) · H330 (categoría 2) · H301 (categoría 3) · y 1 más
Reglamento de cosméticos de la UE, anexo III (sustancias restringidas), entrada 2a · concentración máxima (a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid · se aplica a (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
Restriction III/2a · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Thioglycolic acid and its salts (TGA)
Reviewed by CIR: Final Report on the Safety Assessment of Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid
Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid
Más datos: nombres, identificadores, propiedades, ensayos y literatura
Nombres y definiciones oficiales
Nombre de etiquetado de la JCIA チオグリコール酸: 本品は、次の化学式で表される有機酸である。
Nombres e identificadores
- CAS No.número de registro químico
- 68-11-1
- EC No.número de inventario químico de la UE
- 200-677-4
- DTXSIDidentificador químico de la EPA (EE. UU.)
- DTXSID8026141
- DTXCIDidentificador de compuesto de la EPA (EE. UU.)
- DTXCID406141
- IUPAC
- Sulfanylacetic acid
- Fórmula molecular
- C2H4O2S
- Peso molecular
- 92.11 g/mol
Propiedades medidas
- Color
- incoloro
- pH
- 1.6
- Punto de fusión/congelación
- -16.5 ℃
- Punto inicial e intervalo de ebullición
- 120 ℃
- Punto de inflamación
- 126 ℃(o.c.)
- Límites superior/inferior de inflamabilidad o explosividad
- 5.9 / - % (in air)
- Presión de vapor
- 0.0868 ㎜Hg(25℃)
- Solubilidad en agua
- 100 g/100㎖(25℃)
- Densidad de vapor
- 3.18
- Densidad relativa
- 1.3 (20℃)
- Coeficiente de reparto n-octanol/agua (Kow)
- -2.99
- Temperatura de autoignición
- 350 ℃
- Viscosidad
- 6.55 mPa S(20℃, mPa s)
- Peso molecular
- 92.1
Valores medidos en la sustancia en sí. Los datos de KOSHA son una referencia para redactar y revisar fichas de seguridad, no una especificación de una materia prima comercial.
Para qué lo usan los productos
Usos de los 23 productos declarados ante la EPA de EE. UU. con este ingrediente. Incluye productos que no son cosméticos, así que las primeras filas son sus usos principales.
- Depilatory (EPA)9
- Reducing agent5
- Hair waving or straightening (EPA)1
- Catalyst1
- Surfactant (surface active agent)1
- Processing aids not otherwise specified1
- Flotation agent1
- Corrosion inhibitor1
3 usos más
- Antioxidant1
- Heat stabilizer1
- Intermediate1
Fuente: Panel CompTox de la EPA
Estudios de irritación y sensibilización
Constan 10 estudios en piel y 2 en ojos.
Las conclusiones de los estudios coinciden en general (100%). Son ensayos de la materia prima en sí; la irritación a la cantidad de un producto terminado es otra cuestión.
Ver los 12 estudios
- Skin sensitization - Category 1
Skin Sensitization · Screening - Skin corrosion - category 1
Skin Irritation · Screening - Sh
Skin Sensitization · Authoritative - Skin sensitisation - category 1
Skin Sensitization · Screening - Category 1
Skin Sensitization · Screening - Category 1
Skin Irritation · Screening - Category 8.2C (Category 1C)
Skin Irritation · Read Across - Corrosive
skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to - Skin Corr. 1B
Skin Irritation · Authoritative - Skin corrosion/irritation - Category 1
Skin Irritation · Screening - Category 1
Eye Irritation · Screening - Category 8.3A (Category 1)
Eye Irritation · Read Across
Fuente: Panel CompTox de la EPA
Literatura relacionada
- Effect of Thioglycolic Acid Instillation to Stop Hair Growth on the Urethral Mucosa after Urethroplasty with Hairy Skin in a Rat Model · 2010
- Thioglycolic acid peeling as a therapy for post-inflammatory hyperchromia · 2015
- A Study on a Method of Detecting Heavy Metal Content Using Thioglycolic Acid and Quartz Crucible · 2024
- Colorimetric detection of thioglycolic acid based on the enhanced Fe3+ ions Fenton reaction · 2019
- A Survey on Health Effects in a Human Population Exposed to Permanent‐Waving Solution Containing Thioglycolic Acid · 2003
Bases de datos vinculadas 30
- Base de datos química DSSTox de la EPA
- Búsqueda bibliográfica Tlooto 2 3 4 5
- ChEBI
- ChEMBL
- Cosmetic Ingredient Review (CIR, EE. UU.) 2 3
- Diccionario de ingredientes de la Asociación Coreana de Cosméticos
- Dictámenes de seguridad del SCCS (UE)
- Directiva cosmética de la ASEAN
- Fichas de datos de seguridad de KOSHA (Corea)
- Identificador único de ingredientes de la FDA (UNII)
- Identificadores cruzados UniChem
- Información regulatoria cosmética del MFDS (Corea) 2 3 4
- Ingredientes cosméticos de la FDA de Taiwán
- Inventario de ingredientes de China (IECIC)
- Inventario de productos químicos de Australia (AICIS)
- Lista de ingredientes CosIng (UE) 2
- Lista de ingredientes restringidos de Health Canada
- NIST Chemistry WebBook
- Nombres de etiquetado de la JCIA (Japón)
- Normativa cosmética de la FDA de Taiwán
- Normativa cosmética del Reino Unido (OPSS)
- Panel CompTox de la EPA 2
- PubChem
- Registro de ingredientes cosméticos del MFDS (Corea) 2
- Registro de sustancias de la FDA (GSRS)
- Registro GHS de sustancias tóxicas de Corea (NIER)
- Reglamento de cosméticos de la UE
- Sustancias restringidas UE (anexo III)
- Wikidata
- Wikipedia · inglés · japonés · chino