Gloshell
成分辞典

成分辞典

チオグリコール酸

THIOGLYCOLIC ACID

Thioglycolic acid is a sulfur-containing carboxylic acid.

分子構造

製品には実際どれくらい入っているか

この成分の含有量を表示した製品はまだありません。

この成分を含む製品のうち1件は全成分の前の方(1%ラインより前)、1件は後ろ(ふつう1%以下)に書いています。

この成分を含む製品

確認済み 2件中 2件 · 十分に入っている製品から

定義

Thioglycolic acid is a sulfur-containing carboxylic acid. It is a conjugate acid of a thioglycolate(1-).

出典: PubChem

米国FDA 物質登録 · UNII 7857H94KHM · 登録名 Thioglycolic acid · 単一の化学物質

出典: 米国FDA 物質識別番号(UNII)

Thioglycolic Acid is the organic acid that conforms generally to the formula:

化粧品での役割

他の成分を還元するREDUCING毛を溶かして除去するDEPILATORY髪をカールまたはストレートにするHAIR WAVING OR STRAIGHTENING酸素による劣化を遅らせるANTIOXIDANT

安全性・規制情報

制限
イギリス · 韓国

出典: ASEAN 化粧品指令 · EU 化粧品規則 · カナダ 禁止・制限成分リスト · 韓国食薬処 化粧品規制情報 · 台湾FDA 化粧品成分 · 台湾FDA 化粧品規制 · 英国 化粧品規則

アルゼンチン · ブラジル

  • Field of application and/or use : (a) Products for hair straightening or waving: 1. General use 2. Professional use (b) Depilatories (c) Other products for hair care which are removed after application
  • Maximum concentration permitted at final product : (a) 1. 8% ready to use pH 7 to 9.5 2. 11% ready to use pH 7 to 9.5 (b) 5% ready to use pH 7 to 12.7 (c) 2% .ready to use pH 7 to 9.5 The indicated percentages are calculated as thioglycolic acid
  • Other limitations and requirements : a, b and c) In the USAGE must obligatorily the following information recorded: - Avoid contact with eyes. - In case of contact with eyes, rinse immediately with plenty water and consult a doctor - and c) Wear suitable gloves
  • Use conditions and warnings that must appear on the label : a), b) and c) - Contains thioglycolic acid salts - Follow instructions - Keep out of reach of children - Only for professional use (where appropriate)

ASEAN

  • Field of application and/or use : (a) Hair waving or straightening products: 1. General use 2. Professional use (b) Depilatories (c) Other hair care products which are removed after application
  • Maximum authorised concentration in the finished cosmetic product : (a) 1. 8% ready for use at pH 7 – 9.5 2. 11% ready for use at pH 7- 9.5 (b) 5% ready for use at pH 7-12.7 (c) 2% ready for use at pH 7-9.5 For general use of hair waving or straightening products the maximum concentration for combination of Thioglycolic acid and thiolactic acid must not exceed 8% calculated as Thioglycolic Acid.
  • Other limitations and requirements : (a) (b) (c) The directions for use drawn up in the national or official language(s) must obligatorily incorporate the following sentences: • Avoid contact with eyes • In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice. • Wear suitable gloves (a) and (c) only.
  • Conditions of use and warning which must be printed on the labels : (a) • Contains thioglycolate • Follow the instructions • Keep out of reach of children. • For professional use only. (b) and (c) • Contains thioglycolate • Follow the instructions • Keep out of reach of children

カナダ

  • Conditions of Use by product type : (a) Eyelash curling products (b) Hair dyes, waving or straightening products (c) Hair dyes, waving or straightening products for professional use (d) Depilatory products
  • Maximum Concentration Permitted : ((a) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (b) 8% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (c) 11% (as thioglycolic aci(d) with a pH less than or equal to 9.5 (d) 5% (as thioglycolic aci(d) with a pH less than or equal to 12.7
  • Warnings and Cautionary Statements: (to the effect of) : (a) "For professional use only.", "Avoid direct skin contact, wear suitable gloves.", "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention." (b)"Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." (c) "For professional use only." "Avoid direct skin contact, wear suitable gloves.", "Not for use in the area of the eye." d) "Avoid contact with eyes and, in the event of contact with eyes, rinse immediately with plenty of water and seek medical attention."

台湾

  • ※ 染髮產品之限量標準:係指該成分依產品使用說明書混合後之最高允許使用量。
  • ※ 化粧品之外包裝或容器,應明顯標示本表所列成分之注意事項。因外包裝或容器表面積過小或其他特殊情形致不能標示者,應於標籤、仿單或以其他方式刊載之。
  • ※ 本表所稱之口腔製劑,包含非藥用牙膏、漱口水類及美白牙齒類等化粧品。
  • ※ 化粧品宣稱效能者,須符合化粧品標示宣傳廣告涉及虛偽誇大或醫療效能認定準則規定。
  • 用途 : 使用限制
  • 最大配合量 : (a)燙髮產品 : (a1)8% (以thioglycollic acid 計)
  • (a2)11% (以 thioglycollic acid 計)
  • (b)立即沖洗之髮用產品 : 2%( 以 thioglycollic acid 計)
  • (a2)11%
  • (b)含 thioglycolate; 使用前請詳閱說明書,並依據使用方法正確使用;應放置於孩童伸手不及之場所儲存。

中国

  • 最大配合量 : (a)

欧州連合

  • Product Type, body parts : (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving
  • Maximum concentration in ready for use preparation : (a) 1) 8% 2) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid
  • Other : (a) General use ready for use pH 7 to 9.5 Professional use ready for use pH 7 to 9.5 (b) ready for use pH 7 to 12.7 (c) ready for use pH 7 to 9.5 (d) ready for use pH 7 to 9,5
  • Wording of conditions of use and warnings : Condition of use: (a) (b) (c) Avoid contact with eyes In the event of contact with eyes, rinse immediately with plenty of water and seek medical advice (a) (c) (d) Wear suitable gloves Warnings to be printed on the label: (a) (b) (c) Contains thioglycolate Follow the instructions Keep out of reach of children (a) (d) For professional use only: Cotains thiglycolata, folow the instruction.

出典: 韓国食薬処 化粧品規制情報

韓国の有害物質GHS分類: 危険 · H311 (区分3) · H330 (区分2) · H301 (区分3) · ほか1件

出典: 韓国 有害物質GHS情報(環境公団)

EU化粧品規則 附属書III(制限物質) 第2a項 · 最大濃度 (a) (i) 8% (ii) 11% (b) 5% (c) 2% (d) 11% The abovementioned percentages are calculated as thioglycollic acid · 適用 (a) Hair products (b) Depilatories (c) Hair rinse-off products (d) Products intended for eyelash waving

出典: EU 制限成分(附属書III)

Restriction III/2a · Other restriction: ban substances that deplete the ozone layer · SCCS opinion: Thioglycolic acid and its salts (TGA)

出典: EU CosIng 成分リスト

Reviewed by CIR: Final Report on the Safety Assessment of Ammonium and Glyceryl Thioglycolates and Thioglycolic Acid

出典: 米国CIR 安全性評価

Reviewed by CIR: Final Amended Report on the Safety Assessment of Ammonium Thioglycolate, Butyl Thioglycolate, Calcium Thioglycolate, Ethanolamine Thioglycolate, Ethyl Thioglycolate, Glyceryl Thioglycolate, Isooctyl Thioglycolate, Isopropyl Thioglycolate, Magnesium Thioglycolate, Methyl Thioglycolate, Potassium Thioglycolate, Sodium Thioglycolate, and Thioglycolic Acid

出典: 米国CIR 安全性評価

詳しい資料 — 表示名・識別番号・物性・試験記録・文献

公式表示名・定義

日本化粧品工業会の表示名称 チオグリコール酸: 本品は、次の化学式で表される有機酸である。

出典: 日本化粧品工業会 表示名称

別名・識別情報

THIOGLYCOLIC ACIDINCI치오글라이콜릭애씨드韓国の表示名(食薬処標準名)Acetic acid, 2-mercapto-別名チオグリコール酸日本の表示名称
CAS No.化学物質登録番号
68-11-1
EC No.EU化学物質目録番号
200-677-4
DTXSID米国EPA化学物質番号
DTXSID8026141
DTXCID米国EPA化合物番号
DTXCID406141
IUPAC
Sulfanylacetic acid
分子式
C2H4O2S
分子量
92.11 g/mol

測定された物性

色
無色
pH
1.6
融点・凝固点
-16.5 ℃
初留点および沸点範囲
120 ℃
引火点
126 ℃(o.c.)
燃焼・爆発範囲の上限/下限
5.9 / - % (in air)
蒸気圧
0.0868 ㎜Hg(25℃)
溶解度
100 g/100㎖(25℃)
蒸気密度
3.18
比重
1.3 (20℃)
n-オクタノール/水分配係数(Kow)
-2.99
自然発火温度
350 ℃
粘度
6.55 mPa S(20℃, mPa s)
分子量
92.1

物質そのものを測定した値です。安全保健公団(KOSHA)の資料はSDS作成・確認の参考用で、原料商品の規格ではありません。

出典: 韓国安全保健公団 SDS

製品が実際に使っている用途

米国EPAにこの成分を届け出た製品23件の用途です。化粧品以外の製品も含まれるため、上の数行がこの成分の主な使い道といえます。

  • Depilatory (EPA)9
  • Reducing agent5
  • Hair waving or straightening (EPA)1
  • Catalyst1
  • Surfactant (surface active agent)1
  • Processing aids not otherwise specified1
  • Flotation agent1
  • Corrosion inhibitor1
その他の用途 3件
  • Antioxidant1
  • Heat stabilizer1
  • Intermediate1

出典: 米国EPA CompTox

刺激・感作試験の記録

皮膚試験10件・眼試験2件の記録があります。

刺激が強いと分類1件

試験の結論はおおむね一致しています(100%)。 原料そのものを試験した記録で、完成品に含まれる濃度での刺激性とは異なります。

試験12件をすべて見る
  • Skin sensitization - Category 1
    Skin Sensitization · Screening
  • Skin corrosion - category 1
    Skin Irritation · Screening
  • Sh
    Skin Sensitization · Authoritative
  • Skin sensitisation - category 1
    Skin Sensitization · Screening
  • Category 1
    Skin Sensitization · Screening
  • Category 1
    Skin Irritation · Screening
  • Category 8.2C (Category 1C)
    Skin Irritation · Read Across
  • Corrosive
    skin irritation: in vivo · Screening · OECD Guideline 404 (Acute Dermal Irritation / Corrosion) equivalent or similar to
  • Skin Corr. 1B
    Skin Irritation · Authoritative
  • Skin corrosion/irritation - Category 1
    Skin Irritation · Screening
  • Category 1
    Eye Irritation · Screening
  • Category 8.3A (Category 1)
    Eye Irritation · Read Across

出典: 米国EPA CompTox

関連文献

連携データベース 30