Ingredient Dictionary

THIOSALICYLIC ACID

Thiosalicylic acid is a sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid.

Definition

Thiosalicylic acid is a sulfanylbenzoic acid that is the 2-sulfanyl derivative of benzoic acid. It has a role as a non-narcotic analgesic and an antipyretic. It is a conjugate acid of a thiosalicylate(1-).

Source: PubChem

US FDA substance register · UNII CIP6LXN5XW · registered name THIOSALICYLIC ACID · single chemical substance

Source: US FDA Unique Ingredient Identifier (UNII)

Cosmetic roles

Slows spoilage by oxygenANTIOXIDANTSoftens and loosens the outer layerKERATOLYTICReduces other ingredientsREDUCING

Safety & regulatory references

Not classified under Korea’s toxic-substance GHS list · existing chemical substance

Source: Korea toxic substances GHS register (NIER)

Other restriction: ban substances that deplete the ozone layer

Source: EU CosIng ingredient list

More data — names, identifiers, properties, test records, literature

Names & identifiers

THIOSALICYLIC ACIDINCI티오살리실릭애씨드Korean label name (MFDS standard)Benzoic acid, 2-mercapto-Synonym

CAS No.chemical registry number: 147-93-3
EC No.EU chemical inventory number: 205-704-3
DTXSIDUS EPA chemical ID: DTXSID4049032
DTXCIDUS EPA compound ID: DTXCID5028958

IUPAC: 2-Sulfanylbenzoic acid
Molecular formula: C7H6O2S
Molecular weight: 154.18 g/mol

Measured properties

Appearance: Sulfur-yellow solid, Slightly soluble in hot water, [Merck Index] Yellow powder, soluble in water, [MSDSonline] · SULFUR-YELLOW FLAKES, PLATES, NEEDLES FROM GLACIAL ACETIC ACID OR ALCOHOL
Melting point: 168-169 °C
Solubility: SOL IN WATER /SODIUM SALT/ · SOL IN HOT WATER, ALCOHOL, ETHER, ACETIC ACID, SLIGHTLY SOLUBLE IN PETROLEUM ETHER
Stability: EXPOSURE TO AIR YIELDS DITHIOSALICYLIC ACID
Melting/freezing point: 164~169 ℃
Molecular weight: 154.19

Values measured on the substance itself. The KOSHA data are a reference for writing and reviewing safety data sheets, not a specification for a commercial raw material.

Source: PubChem · KOSHA safety data sheets (Korea)

What products actually use it for

What the 3 products reported to the US EPA with this ingredient use it for. Products outside cosmetics are included, so the top few rows are its main uses.

Reducing agent1
Pharmaceutical (EPA)1
Antioxidant1

Source: US EPA CompTox dashboard

Irritation and sensitisation studies

1 skin studies and 1 eye studies are on record.

Classed as moderate1

The study conclusions largely agree (100%). These tests are on the raw material itself; irritation at the amount in a finished product is a different question.

See all 2 studies

Category 6.3A (Category 2)
Skin Irritation · Read Across
Category 6.4A (Category 2A)
Eye Irritation · Read Across